Literature DB >> 2408659

Retinal pigment epithelial detachments in the elderly: classification and outcome.

A G Casswell, D Kohen, A C Bird.   

Abstract

Sixty-four eyes of 57 elderly patients with pigment epithelial detachments (PEDs) were studied with the aim of describing their morphological features and identifying prognostic factors. They were classified into four groups according to the following characteristics: early fluorescence, late fluorescence, shallow detachment with limited fluorescence ('drusen type'), irregular fluorescence. The following conclusions were drawn: 30% developed demonstrable subretinal new vessels; all groups except the drusen type were susceptible, the irregular group being particularly prone. 10% developed retinal pigment epithelial tears, and these occurred almost exclusively in the slow fluorescent group. Flattening of PEDs was a feature of drusen type and early fluorescent groups. Most patients lost vision. RPE tears occurred within a few months of presentation with immediate loss of vision; likewise rapid loss of vision followed the development of demonstrable new vessels, though not necessarily in those with changes thought to imply the presence of new vessels. Flattening after prolonged detachment was associated with pigment epithelial atrophy and invariable loss of vision. Visual acuity was maintained consistently only in those eyes with persistent detachment.

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Mesh:

Year:  1985        PMID: 2408659      PMCID: PMC1040616          DOI: 10.1136/bjo.69.6.397

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  3 in total

1.  Natural history of serous detachments of the retinal pigment epithelium.

Authors:  T A Meredith; R E Braley; T M Aaberg
Journal:  Am J Ophthalmol       Date:  1979-10       Impact factor: 5.258

2.  Idiopathic serous detachment of the retinal pigment epithelium.

Authors:  M L Lewis
Journal:  Arch Ophthalmol       Date:  1978-04

3.  Tears of detached retinal pigment epithelium.

Authors:  A Hoskin; A C Bird; K Sehmi
Journal:  Br J Ophthalmol       Date:  1981-06       Impact factor: 4.638

  3 in total
  48 in total

1.  [Effect of intravitreal bevacizumab on pigment epithelial detachment in occult choroidal neovascularization].

Authors:  M Ruppenstein; T Ach; A Höh; S Dithmar
Journal:  Ophthalmologe       Date:  2010-09       Impact factor: 1.059

2.  Detection of subpigment epithelial neovascularisation in cases of retinal pigment epithelial detachments: a review of the Moorfields treatment trial.

Authors:  S Pagliarini; M J Barondes; I H Chisholm; A M Hamilton; A C Bird
Journal:  Br J Ophthalmol       Date:  1992-01       Impact factor: 4.638

3.  Acute tear of the retinal pigment epithelium.

Authors:  B C Patel; M Barondes; A M Hamilton
Journal:  Int Ophthalmol       Date:  1992-01       Impact factor: 2.031

4.  Classification of retinal pigment epithelial detachments associated with drusen.

Authors:  M E Hartnett; J J Weiter; A Garsd; A E Jalkh
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1992       Impact factor: 3.117

Review 5.  Bruch's membrane change with age.

Authors:  A C Bird
Journal:  Br J Ophthalmol       Date:  1992-03       Impact factor: 4.638

6.  Computerised visual field deficits in tears of the retinal pigment epithelium.

Authors:  J I Maguire; W H Annesley; W L Decker; G C Brown; D H Fischer; J M Slagle
Journal:  Br J Ophthalmol       Date:  1990-09       Impact factor: 4.638

Review 7.  [Pigment epithelial detachment in exudative macular degeneration: clinical characteristics and therapeutic options].

Authors:  A Lommatzsch
Journal:  Ophthalmologe       Date:  2010-12       Impact factor: 1.059

8.  Multimodal evaluation of macular function in age-related macular degeneration.

Authors:  Ken Ogino; Akitaka Tsujikawa; Kenji Yamashiro; Sotaro Ooto; Akio Oishi; Isao Nakata; Masahiro Miyake; Ayako Takahashi; Abdallah A Ellabban; Nagahisa Yoshimura
Journal:  Jpn J Ophthalmol       Date:  2013-12-12       Impact factor: 2.447

Review 9.  Complement activation and choriocapillaris loss in early AMD: implications for pathophysiology and therapy.

Authors:  S Scott Whitmore; Elliott H Sohn; Kathleen R Chirco; Arlene V Drack; Edwin M Stone; Budd A Tucker; Robert F Mullins
Journal:  Prog Retin Eye Res       Date:  2014-12-05       Impact factor: 21.198

10.  Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17.

Authors:  Jeannette J Yu; Elvira Agrón; Traci E Clemons; Amitha Domalpally; Freekje van Asten; Tiarnan D Keenan; Catherine Cukras; Emily Y Chew
Journal:  Ophthalmology       Date:  2018-08-22       Impact factor: 12.079

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