Literature DB >> 24086076

Studies of morphogens: keep calm and carry on.

Angelike Stathopoulos1, Dagmar Iber.   

Abstract

Morphogens are signaling factors that direct cell fate and tissue development at a distance from their source, and various modes of transport and interpretation have been suggested for morphogens. The recent EMBO Workshop on 'Morphogen gradients', which took place in Oxford, UK in June 2013, centered on the formation and interpretation of such morphogen gradients during development. This meeting allowed an exchange of views in light of recent results. Here, we provide a brief overview of the talks, organized in relation to several major themes of discussion at the meeting: (1) morphogen gradient formation; (2) morphogen gradient interpretation; (3) signaling networks and feedback in morphogenesis; (4) emergence of patterns; (5) scaling of patterns; (6) the control of growth; and (7) new techniques in the field.

Keywords:  Cell fate; Morphogens; Tissue development

Mesh:

Substances:

Year:  2013        PMID: 24086076      PMCID: PMC3787753          DOI: 10.1242/dev.095141

Source DB:  PubMed          Journal:  Development        ISSN: 0950-1991            Impact factor:   6.868


  42 in total

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Review 2.  How cells know where they are.

Authors:  Arthur D Lander
Journal:  Science       Date:  2013-02-22       Impact factor: 47.728

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4.  Hox genes regulate digit patterning by controlling the wavelength of a Turing-type mechanism.

Authors:  Rushikesh Sheth; Luciano Marcon; M Félix Bastida; Marisa Junco; Laura Quintana; Randall Dahn; Marie Kmita; James Sharpe; Maria A Ros
Journal:  Science       Date:  2012-12-14       Impact factor: 47.728

Review 5.  Investigating the principles of morphogen gradient formation: from tissues to cells.

Authors:  Anna Kicheva; Tobias Bollenbach; Ortrud Wartlick; Frank Jülicher; Marcos Gonzalez-Gaitan
Journal:  Curr Opin Genet Dev       Date:  2012-09-06       Impact factor: 5.578

6.  Self-organized shuttling: generating sharp dorsoventral polarity in the early Drosophila embryo.

Authors:  Michal Haskel-Ittah; Danny Ben-Zvi; Merav Branski-Arieli; Eyal D Schejter; Ben-Zion Shilo; Naama Barkai
Journal:  Cell       Date:  2012-08-31       Impact factor: 41.582

7.  Scaling of embryonic patterning based on phase-gradient encoding.

Authors:  Volker M Lauschke; Charisios D Tsiairis; Paul François; Alexander Aulehla
Journal:  Nature       Date:  2012-12-19       Impact factor: 49.962

8.  Morphogen transport.

Authors:  Patrick Müller; Katherine W Rogers; Shuizi R Yu; Michael Brand; Alexander F Schier
Journal:  Development       Date:  2013-04       Impact factor: 6.868

Review 9.  How to build a robust intracellular concentration gradient.

Authors:  Martin Howard
Journal:  Trends Cell Biol       Date:  2012-04-13       Impact factor: 20.808

10.  Transport of fibroblast growth factor 2 in the pericellular matrix is controlled by the spatial distribution of its binding sites in heparan sulfate.

Authors:  Laurence Duchesne; Vivien Octeau; Rachel N Bearon; Alison Beckett; Ian A Prior; Brahim Lounis; David G Fernig
Journal:  PLoS Biol       Date:  2012-07-17       Impact factor: 8.029

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  10 in total

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Journal:  Proc Natl Acad Sci U S A       Date:  2015-08-03       Impact factor: 11.205

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Authors:  Yangxiaolu Cao; Marc D Ryser; Stephen Payne; Bochong Li; Christopher V Rao; Lingchong You
Journal:  Cell       Date:  2016-04-21       Impact factor: 41.582

3.  Rapid translocation of pluripotency-related transcription factors by external uniaxial forces.

Authors:  Tuğba Topal; Byoung Choul Kim; Luis G Villa-Diaz; Cheri X Deng; Shuichi Takayama; Paul H Krebsbach
Journal:  Integr Biol (Camb)       Date:  2019-02-26       Impact factor: 2.192

Review 4.  Mechanobiology of cells and cell systems, such as organoids.

Authors:  Ece Bayir; Aylin Sendemir; Yannis F Missirlis
Journal:  Biophys Rev       Date:  2019-09-09

5.  Changes in lipid profile and SOX-2 expression in RM-1 cells after co-culture with preimplantation embryos or with deproteinated blastocyst extracts.

Authors:  Nicolás M Morato; Judy E Hallett; Wen-Hung Wang; Bennett D Elzey; Gregory M Cresswell; Bruce R Cooper; Christina R Ferreira
Journal:  Mol Omics       Date:  2022-07-11

6.  Visualizing retinoic acid morphogen gradients.

Authors:  T F Schilling; J Sosnik; Q Nie
Journal:  Methods Cell Biol       Date:  2016-04-18       Impact factor: 1.441

Review 7.  CD44, Hyaluronan, the Hematopoietic Stem Cell, and Leukemia-Initiating Cells.

Authors:  Margot Zöller
Journal:  Front Immunol       Date:  2015-05-26       Impact factor: 7.561

Review 8.  Novel insights into the development and maintenance of the blood-brain barrier.

Authors:  Britta Engelhardt; Stefan Liebner
Journal:  Cell Tissue Res       Date:  2014-03-04       Impact factor: 5.249

9.  Predicted molecular signaling guiding photoreceptor cell migration following transplantation into damaged retina.

Authors:  Uchenna John Unachukwu; Alice Warren; Ze Li; Shawn Mishra; Jing Zhou; Moira Sauane; Hyungsik Lim; Maribel Vazquez; Stephen Redenti
Journal:  Sci Rep       Date:  2016-03-03       Impact factor: 4.379

10.  3 minutes to precisely measure morphogen concentration.

Authors:  Tanguy Lucas; Huy Tran; Carmina Angelica Perez Romero; Aurélien Guillou; Cécile Fradin; Mathieu Coppey; Aleksandra M Walczak; Nathalie Dostatni
Journal:  PLoS Genet       Date:  2018-10-26       Impact factor: 5.917

  10 in total

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