Literature DB >> 2408344

Human alpha 2-macroglobulin gene is located on chromosome 12.

G I Bell, L B Rall, R Sanchez-Pescador, J P Merryweather, J Scott, R L Eddy, T B Shows.   

Abstract

A cDNA clone encoding amino acids 809-1451 of the protease inhibitor alpha 2-macroglobulin has been isolated from an adult human liver cDNA library. This cDNA was used to examine DNA samples prepared from a panel of human-mouse somatic cell hybrids with different numbers and combinations of human chromosomes for the presence of the human alpha 2-macroglobulin gene. The cosegregation of this gene and chromosome 12 in the cell hybrid panel indicated that the alpha 2-macroglobulin structural gene (designated A2M) is on human chromosome 12.

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Year:  1985        PMID： 2408344     DOI： 10.1007/bf01534685

Source DB:  PubMed          Journal:  Somat Cell Mol Genet        ISSN： 0740-7750


  5 in total

1.  Assignment of mouse alpha-2-macroglobulin gene to chromosome 6 band F1-G3.

Authors:  C Hilliker; L Overbergh; P Petit; F Van Leuven; H Van den Berghe
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  Localization of the α2-macroglobulin gene and Lpm gene family on mink chromosome 9.

Authors:  V I Yermolaev; G I Karasik; T M Khlebodarova; N M Matveeva; M R Mullakandov; A M Nayakschin; T V Shumny; N B Rubtsov; O L Serov; O K Baranov
Journal:  Theor Appl Genet       Date:  1989-07       Impact factor: 5.699

3.  Detection of an alteration of the alpha 2-macroglobulin gene in a patient with chronic lung disease and serum alpha 2-macroglobulin deficiency.

Authors:  W Poller; J Barth; B Voss
Journal:  Hum Genet       Date:  1989-08       Impact factor: 4.132

4.  Three RFLPs associated with the human alpha 2-macroglobulin gene (A2M).

Authors:  P Marynen; G I Bell; L L Cavalli-Sforza
Journal:  Nucleic Acids Res       Date:  1985-11-25       Impact factor: 16.971

5.  Differential regulation of the JE gene encoding the monocyte chemoattractant protein (MCP-1) in cervical carcinoma cells and derived hybrids.

Authors:  F Rösl; M Lengert; J Albrecht; K Kleine; R Zawatzky; B Schraven; H zur Hausen
Journal:  J Virol       Date:  1994-04       Impact factor: 5.103
  5 in total

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