Literature DB >> 2408338

A new class of endogenous human retroviral genomes.

R Callahan, I M Chiu, J F Wong, S R Tronick, B A Roe, S A Aaronson, J Schlom.   

Abstract

Human DNA contains multiple copies of a novel class of endogenous retroviral genomes. Analysis of a human recombinant DNA clone (HLM-2) containing one such proviral genome revealed that it is a mosaic of retroviral-related sequences with the organization and length of known endogenous retroviral genomes. The HLM-2 long terminal repeat hybridized with the long terminal repeat of the squirrel monkey virus, a type D retrovirus. The HLM-2 gag and pol genes share extensive nucleotide sequence homology with those of the M432 retrovirus (a type A-related retrovirus), mouse mammary tumor virus (a type B retrovirus), and the avian Rous sarcoma virus (a type C retrovirus). Nucleotide sequence analysis revealed regions in the HLM-2 pol gene that were as much as 70 percent identical to the mouse mammary tumor virus pol gene. A portion of the putative HLM-2 env gene hybridized with the corresponding region of the M432 viral genome.

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Year:  1985        PMID： 2408338     DOI： 10.1126/science.2408338

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  39 in total

1.  Identification of regulatory elements within the minimal promoter region of the human endogenous ERV9 proviruses: accurate transcription initiation is controlled by an Inr-like element.

Authors:  G La Mantia; B Majello; A Di Cristofano; M Strazzullo; G Minchiotti; L Lania
Journal:  Nucleic Acids Res       Date:  1992-08-25       Impact factor: 16.971

2.  Identification and characterization of novel human endogenous retroviral sequences prefentially expressed in undifferentiated embryonal carcinoma cells.

Authors:  G La Mantia; D Maglione; G Pengue; A Di Cristofano; A Simeone; L Lanfrancone; L Lania
Journal:  Nucleic Acids Res       Date:  1991-04-11       Impact factor: 16.971

3.  cDNA clones encoding murine IgE-binding factors represent multiple structural variants of intracisternal A-particle genes.

Authors:  E L Kuff; J A Mietz; M L Trounstine; K W Moore; C L Martens
Journal:  Proc Natl Acad Sci U S A       Date:  1986-09       Impact factor: 11.205

4.  A new family of LTR-like sequences abundantly expressed in rat tumors.

Authors:  N Suzuki; T Fujiyoshi; Y Maehara; K Takahashi; M Yamamoto; H Endo
Journal:  Nucleic Acids Res       Date:  1986-12-09       Impact factor: 16.971

5.  Molecular cloning and primary structure analysis of the mouse mammary tumor virus-related element from dwarf hamster genome.

Authors:  A T Tikhonenko; N S Vassetzky; T V Golovkina; A V Gudkov
Journal:  Virus Genes       Date:  1990-02       Impact factor: 2.332

6.  A novel human nonviral retroposon derived from an endogenous retrovirus.

Authors:  M Ono; M Kawakami; T Takezawa
Journal:  Nucleic Acids Res       Date:  1987-11-11       Impact factor: 16.971

7.  Molecular cloning and long terminal repeat sequences of human endogenous retrovirus genes related to types A and B retrovirus genes.

Authors:  M Ono
Journal:  J Virol       Date:  1986-06       Impact factor: 5.103

8.  Nucleotide sequence of the intracisternal A-particle genome inserted 5' to the interleukin-3 gene of the leukemia cell line WEHI-3B.

Authors:  S Ymer; W Q Tucker; H D Campbell; I G Young
Journal:  Nucleic Acids Res       Date:  1986-07-25       Impact factor: 16.971

9.  Human endogenous retroviruslike genome with type C pol sequences and gag sequences related to human T-cell lymphotropic viruses.

Authors:  D L Mager; J D Freeman
Journal:  J Virol       Date:  1987-12       Impact factor: 5.103

10.  Identification of a retinoic acid-inducible endogenous retroviral transcript in the human teratocarcinoma-derived cell line PA-1.

Authors:  P Kannan; R Buettner; D R Pratt; M A Tainsky
Journal:  J Virol       Date:  1991-11       Impact factor: 5.103
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