| Literature DB >> 24080871 |
Abstract
The incidence of acute kidney injury (AKI) is increasing. It is now widely accepted that patients surviving an episode of AKI have a significant risk of progression to chronic kidney disease (CKD) and even end-stage renal failure. Zager and colleagues describe the role of endothelin-1 (ET-1) in the progression of AKI to CKD and provide a basis for the potential use of ET receptor antagonists as a therapeutic strategy in AKI.Entities:
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Year: 2013 PMID： 24080871 DOI： 10.1038/ki.2013.158
Source DB: PubMed Journal: Kidney Int ISSN： 0085-2538 Impact factor: 10.612