Literature DB >> 24080792

Risk factors of γ-hydroxybutyrate overdosing.

Dirk J Korf1, Ton Nabben, Annemieke Benschop, Kim Ribbink, Jan G C van Amsterdam.   

Abstract

The aim of this study was to identify in recreational drug users the factors which increase the risk of overdosing (OD) with γ-hydroxybutyrate (GHB). A purposive sample of 45 experienced GHB users was interviewed, equally divided into three groups (never OD, occasional OD, and repeat OD). The repeat OD group scored highest on many risk factors regarding GHB use, the occasional OD group scored intermediate, and the never OD group scored lowest. Participants, whether or not they had overdosed on GHB, most often perceived GHB use (e.g. using more GHB than usual, using GHB doses too closely together) as the main reason for GHB OD, and many participants who had overdosed on GHB reported that they had taken more GHB than usual at their most recent occasion of GHB OD. No significant differences in co-use of GHB with other substances were found between the three groups. Our findings indicate that using GHB in the company of groups of friends probably reduces, but does not eliminate, the risk of OD.
© 2013 S. Karger AG, Basel.

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Year:  2013        PMID: 24080792     DOI: 10.1159/000353237

Source DB:  PubMed          Journal:  Eur Addict Res        ISSN: 1022-6877            Impact factor:   3.015


  4 in total

1.  Influence of Gamma-Hydroxybutyric Acid-Use and Gamma-Hydroxybutyric Acid-Induced Coma on Affect and the Affective Network.

Authors:  Filipa Raposo Pereira; Minni T B McMaster; Yvon D A T de Vries; Nikki Polderman; Wim van den Brink; Guido A van Wingen
Journal:  Eur Addict Res       Date:  2019-04-18       Impact factor: 3.015

2.  Recreational use of GHB is associated with alterations of resting state functional connectivity of the central executive and default mode networks.

Authors:  Filipa Raposo Pereira; Paul Zhutovsky; Minni T B Mcmaster; Nikki Polderman; Yvon D A T de Vries; Wim van den Brink; Guido A van Wingen
Journal:  Hum Brain Mapp       Date:  2019-02-05       Impact factor: 5.038

3.  Effects of Recreational GHB Use and Multiple GHB-Induced Comas on Brain Structure and Impulsivity.

Authors:  Filipa Raposo Pereira; Minni T B McMaster; Arnt Schellekens; Nikki Polderman; Yvon D A T de Vries; Wim van den Brink; Guido A van Wingen
Journal:  Front Psychiatry       Date:  2020-04-02       Impact factor: 4.157

4.  Effect of GHB-use and GHB-induced comas on dorsolateral prefrontal cortex functioning in humans.

Authors:  Filipa Raposo Pereira; Minni T B McMaster; Nikki Polderman; Yvon D A T de Vries; Wim van den Brink; Guido A van Wingen
Journal:  Neuroimage Clin       Date:  2018-09-26       Impact factor: 4.881

  4 in total

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