Literature DB >> 24080739

TB treatment in a chronic complex emergency: treatment outcomes and experiences in Somalia.

Karin Fischer Liddle1, Riekje Elema, Sein Sein Thi, Jane Greig, Sarah Venis.   

Abstract

BACKGROUND: Médecins Sans Frontières (MSF) provides TB treatment in Galkayo and Marere in Somalia. MSF international supervisory staff withdrew in 2008 owing to insecurity but maintained daily communication with Somali staff. In this paper, we aimed to assess the feasibility of treating TB in a complex emergency setting and describe the programme adaptations implemented to facilitate acceptable treatment outcomes.
METHODS: Routinely collected treatment data from 2005-2012 were retrospectively analysed. In multivariate analyses, factors associated with successful outcome (cure or completion versus failure, death and default) were assessed, including the presence of international supervisory staff. Informal interviews were conducted with Somali staff regarding programmatic factors affecting patient management and perceived reasons for default.
RESULTS: In total, 6167 patients were admitted (34.8% female; median age 24.0 years [IQR 13.0-38.0 years]). Treatment success was 79% (programme range 69-87%). Presence of international staff did not improve outcomes (adjusted OR 0.85, 95% CI 0.66-1.09; p=0.27). Perceived reasons for default included being away from family, nomadic group, insecurity, travel cost, need to return to grazing land or feeling better.
CONCLUSIONS: Despite the challenges, a high percentage of patients were successfully treated. Treatment outcomes were not adversely affected by withdrawal of international supervisory staff.

Entities:  

Keywords:  Complex emergency; Conflict; Humanitarian; Somalia; Tuberculosis

Mesh:

Substances:

Year:  2013        PMID: 24080739     DOI: 10.1093/trstmh/trt090

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


  6 in total

1.  Directly-observed and self-administered tuberculosis treatment in a chronic, low-intensity conflict setting in India.

Authors:  Mrinalini Das; Petros Isaakidis; Edward Armstrong; Nirmala Rani Gundipudi; Ramesh B Babu; Ihtesham A Qureshi; Andrea Claes; Anil Kumar Mudimanchi; Nagendra Prasad; Homa Mansoor; Sunita Abraham
Journal:  PLoS One       Date:  2014-03-20       Impact factor: 3.240

Review 2.  Visceral leishmaniasis in Somalia: A review of epidemiology and access to care.

Authors:  Temmy Sunyoto; Julien Potet; Marleen Boelaert
Journal:  PLoS Negl Trop Dis       Date:  2017-03-09

3.  Conflict and tuberculosis in Sudan: a 10-year review of the National Tuberculosis Programme, 2004-2014.

Authors:  Sara A Hassanain; Jeffrey K Edwards; Emilie Venables; Engy Ali; Khadiga Adam; Hafiz Hussien; Asma Elsony
Journal:  Confl Health       Date:  2018-05-16       Impact factor: 2.723

4.  Delivering infectious disease interventions to women and children in conflict settings: a systematic reviefw.

Authors:  Sarah Meteke; Marianne Stefopulos; Daina Als; Michelle Gaffey; Mahdis Kamali; Fahad J Siddiqui; Mariella Munyuzangabo; Reena P Jain; Shailja Shah; Amruta Radhakrishnan; Anushka Ataullahjan; Zulfiqar A Bhutta
Journal:  BMJ Glob Health       Date:  2020-04

5.  Somalia: A Nation at the Crossroads of Extreme Poverty, Conflict, and Neglected Tropical Diseases.

Authors:  Annum Jaffer; Peter J Hotez
Journal:  PLoS Negl Trop Dis       Date:  2016-09-29

6.  Risk factors and risk factor cascades for communicable disease outbreaks in complex humanitarian emergencies: a qualitative systematic review.

Authors:  Charlotte Christiane Hammer; Julii Brainard; Paul R Hunter
Journal:  BMJ Glob Health       Date:  2018-07-06
  6 in total

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