Literature DB >> 24078713

ReportingTools: an automated result processing and presentation toolkit for high-throughput genomic analyses.

Melanie A Huntley1, Jessica L Larson, Christina Chaivorapol, Gabriel Becker, Michael Lawrence, Jason A Hackney, Joshua S Kaminker.   

Abstract

UNLABELLED: It is common for computational analyses to generate large amounts of complex data that are difficult to process and share with collaborators. Standard methods are needed to transform such data into a more useful and intuitive format. We present ReportingTools, a Bioconductor package, that automatically recognizes and transforms the output of many common Bioconductor packages into rich, interactive, HTML-based reports. Reports are not generic, but have been individually designed to reflect content specific to the result type detected. Tabular output included in reports is sortable, filterable and searchable and contains context-relevant hyperlinks to external databases. Additionally, in-line graphics have been developed for specific analysis types and are embedded by default within table rows, providing a useful visual summary of underlying raw data. ReportingTools is highly flexible and reports can be easily customized for specific applications using the well-defined API. AVAILABILITY: The ReportingTools package is implemented in R and available from Bioconductor (version ≥ 2.11) at the URL: http://bioconductor.org/packages/release/bioc/html/ReportingTools.html. Installation instructions and usage documentation can also be found at the above URL.

Mesh:

Year:  2013        PMID: 24078713      PMCID: PMC5994940          DOI: 10.1093/bioinformatics/btt551

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  7 in total

1.  Linear models and empirical bayes methods for assessing differential expression in microarray experiments.

Authors:  Gordon K Smyth
Journal:  Stat Appl Genet Mol Biol       Date:  2004-02-12

2.  Reproducible research: a bioinformatics case study.

Authors:  Robert Gentleman
Journal:  Stat Appl Genet Mol Biol       Date:  2005-01-11

3.  Using GOstats to test gene lists for GO term association.

Authors:  S Falcon; R Gentleman
Journal:  Bioinformatics       Date:  2006-11-10       Impact factor: 6.937

4.  Nozzle: a report generation toolkit for data analysis pipelines.

Authors:  Nils Gehlenborg; Michael S Noble; Gad Getz; Lynda Chin; Peter J Park
Journal:  Bioinformatics       Date:  2013-02-17       Impact factor: 6.937

5.  Gene set enrichment analysis using linear models and diagnostics.

Authors:  Assaf P Oron; Zhen Jiang; Robert Gentleman
Journal:  Bioinformatics       Date:  2008-09-11       Impact factor: 6.937

6.  Bioconductor: open software development for computational biology and bioinformatics.

Authors:  Robert C Gentleman; Vincent J Carey; Douglas M Bates; Ben Bolstad; Marcel Dettling; Sandrine Dudoit; Byron Ellis; Laurent Gautier; Yongchao Ge; Jeff Gentry; Kurt Hornik; Torsten Hothorn; Wolfgang Huber; Stefano Iacus; Rafael Irizarry; Friedrich Leisch; Cheng Li; Martin Maechler; Anthony J Rossini; Gunther Sawitzki; Colin Smith; Gordon Smyth; Luke Tierney; Jean Y H Yang; Jianhua Zhang
Journal:  Genome Biol       Date:  2004-09-15       Impact factor: 13.583

7.  edgeR: a Bioconductor package for differential expression analysis of digital gene expression data.

Authors:  Mark D Robinson; Davis J McCarthy; Gordon K Smyth
Journal:  Bioinformatics       Date:  2009-11-11       Impact factor: 6.937

  7 in total
  13 in total

1.  A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains.

Authors:  Patrick C G Haddick; Jessica L Larson; Nisha Rathore; Tushar R Bhangale; Qui T Phung; Karpagam Srinivasan; David V Hansen; Jennie R Lill; Margaret A Pericak-Vance; Jonathan Haines; Lindsay A Farrer; John S Kauwe; Gerard D Schellenberg; Carlos Cruchaga; Alison M Goate; Timothy W Behrens; Ryan J Watts; Robert R Graham; Joshua S Kaminker; Marcel van der Brug
Journal:  J Alzheimers Dis       Date:  2017       Impact factor: 4.472

2.  X-ray irradiation induces subtle changes in the genome-wide distribution of DNA hydroxymethylation with opposing trends in genic and intergenic regions.

Authors:  Benjamin V Becker; Leonhard Kaatsch; Richard Obermair; Gerrit Schrock; Matthias Port; Reinhard Ullmann
Journal:  Epigenetics       Date:  2019-01-29       Impact factor: 4.528

3.  Alterations of microRNAs throughout the malignant evolution of cutaneous squamous cell carcinoma: the role of miR-497 in epithelial to mesenchymal transition of keratinocytes.

Authors:  A Mizrahi; A Barzilai; D Gur-Wahnon; I Z Ben-Dov; S Glassberg; T Meningher; E Elharar; M Masalha; J Jacob-Hirsch; H Tabibian-Keissar; I Barshack; J Roszik; R Leibowitz-Amit; Y Sidi; D Avni
Journal:  Oncogene       Date:  2017-09-18       Impact factor: 9.867

4.  RNA-Seq workflow: gene-level exploratory analysis and differential expression.

Authors:  Michael I Love; Simon Anders; Vladislav Kim; Wolfgang Huber
Journal:  F1000Res       Date:  2015-10-14

5.  Massive Effect on LncRNAs in Human Monocytes During Fungal and Bacterial Infections and in Response to Vitamins A and D.

Authors:  Konstantin Riege; Martin Hölzer; Tilman E Klassert; Emanuel Barth; Julia Bräuer; Maximilian Collatz; Franziska Hufsky; Nelly Mostajo; Magdalena Stock; Bertram Vogel; Hortense Slevogt; Manja Marz
Journal:  Sci Rep       Date:  2017-01-17       Impact factor: 4.379

6.  Differential Analysis of the Nasal Microbiome of Pig Carriers or Non-Carriers of Staphylococcus aureus.

Authors:  Carmen Espinosa-Gongora; Niels Larsen; Kristian Schønning; Merete Fredholm; Luca Guardabassi
Journal:  PLoS One       Date:  2016-08-10       Impact factor: 3.240

7.  Advancements in RNASeqGUI towards a Reproducible Analysis of RNA-Seq Experiments.

Authors:  Francesco Russo; Dario Righelli; Claudia Angelini
Journal:  Biomed Res Int       Date:  2016-02-10       Impact factor: 3.411

8.  Bioconductor's EnrichmentBrowser: seamless navigation through combined results of set- & network-based enrichment analysis.

Authors:  Ludwig Geistlinger; Gergely Csaba; Ralf Zimmer
Journal:  BMC Bioinformatics       Date:  2016-01-20       Impact factor: 3.169

9.  The Ink4a/Arf locus operates as a regulator of the circadian clock modulating RAS activity.

Authors:  Rukeia El-Athman; Nikolai N Genov; Jeannine Mazuch; Kaiyang Zhang; Yong Yu; Luise Fuhr; Mónica Abreu; Yin Li; Thomas Wallach; Achim Kramer; Clemens A Schmitt; Angela Relógio
Journal:  PLoS Biol       Date:  2017-12-07       Impact factor: 8.029

10.  Human plasma and serum extracellular small RNA reference profiles and their clinical utility.

Authors:  Klaas E A Max; Karl Bertram; Kemal Marc Akat; Kimberly A Bogardus; Jenny Li; Pavel Morozov; Iddo Z Ben-Dov; Xin Li; Zachary R Weiss; Azadeh Azizian; Anuoluwapo Sopeyin; Thomas G Diacovo; Catherine Adamidi; Zev Williams; Thomas Tuschl
Journal:  Proc Natl Acad Sci U S A       Date:  2018-05-18       Impact factor: 11.205

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