Literature DB >> 24078173

Fractionated stereotactic radiosurgery for recurrent ependymoma in children.

Lindsey M Hoffman, S Reed Plimpton, Nicholas K Foreman, Nicholas V Stence, Todd C Hankinson, Michael H Handler, Molly S Hemenway, Rajeev Vibhakar, Arthur K Liu.   

Abstract

Outcomes for children with relapsed ependymoma are poor. Re-irradiation is a potentially viable salvage option in these patients. Data were reviewed for 12 patients (median age 5.6 years) with relapsed ependymoma who received fractionated stereotactic radiosurgery (fSRS) following maximal surgical resection from 1995 to 2012. Four patients experienced a second recurrence, including 2 in-field and 2 distant failures. Median time to second recurrence (32 months) was significantly longer than time to first recurrence (24 months) (p = 0.008). Three-year local control was 89 %, and median event free survival from fSRS was 3.4 years. Radiation necrosis was observed in 6 patients, 3 who were symptomatic. In conclusion, fSRS offers durable response with a tolerable toxicity profile in children with recurrent EPN.

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Year:  2014        PMID: 24078173      PMCID: PMC3946261          DOI: 10.1007/s11060-013-1259-3

Source DB:  PubMed          Journal:  J Neurooncol        ISSN: 0167-594X            Impact factor:   4.130


  13 in total

1.  Stereotactic radiosurgery for pediatric recurrent intracranial ependymomas.

Authors:  Hideyuki Kano; Huai-che Yang; Douglas Kondziolka; Ajay Niranjan; Yoshio Arai; John C Flickinger; L Dade Lunsford
Journal:  J Neurosurg Pediatr       Date:  2010-11       Impact factor: 2.375

Review 2.  Salvage chemotherapy for metastatic and recurrent ependymoma of childhood.

Authors:  Eric Bouffet; Michael Capra; Ute Bartels
Journal:  Childs Nerv Syst       Date:  2009-04-10       Impact factor: 1.475

3.  Stereotactic radiosurgery for patients with recurrent intracranial ependymomas.

Authors:  Michael C Stauder; Nadia Ni Laack; Kamran A Ahmed; Michael J Link; Paula J Schomberg; Bruce E Pollock
Journal:  J Neurooncol       Date:  2012-03-23       Impact factor: 4.130

Review 4.  Children's Oncology Group's 2013 blueprint for research: central nervous system tumors.

Authors:  Amar Gajjar; Roger J Packer; N K Foreman; Kenneth Cohen; Daphne Haas-Kogan; Thomas E Merchant
Journal:  Pediatr Blood Cancer       Date:  2012-12-19       Impact factor: 3.167

5.  Recurrent intracranial ependymomas in children. Survival, patterns of failure, and prognostic factors.

Authors:  J W Goldwein; T A Glauser; R J Packer; J L Finlay; L N Sutton; W J Curran; J M Laehy; L B Rorke; L Schut; G J D'Angio
Journal:  Cancer       Date:  1990-08-01       Impact factor: 6.860

6.  Maximally safe resection followed by hypofractionated re-irradiation for locally recurrent ependymoma in children.

Authors:  Arthur K Liu; Nicholas K Foreman; Laurie E Gaspar; Elizabeth Trinidad; Michael H Handler
Journal:  Pediatr Blood Cancer       Date:  2009-07       Impact factor: 3.167

7.  A retrospective study of surgery and reirradiation for recurrent ependymoma.

Authors:  Thomas E Merchant; Frederick A Boop; Larry E Kun; Robert A Sanford
Journal:  Int J Radiat Oncol Biol Phys       Date:  2008-05-01       Impact factor: 7.038

8.  Second-look surgery for incompletely resected fourth ventricle ependymomas: technical case report.

Authors:  N K Foreman; S Love; S S Gill; H B Coakham
Journal:  Neurosurgery       Date:  1997-04       Impact factor: 4.654

9.  Hypofractionation regimens for stereotactic radiotherapy for large brain tumors.

Authors:  Jiankui Yuan; Jian Z Wang; Simon Lo; John C Grecula; Mario Ammirati; Joseph F Montebello; Hualin Zhang; Nilendu Gupta; William T C Yuh; Nina A Mayr
Journal:  Int J Radiat Oncol Biol Phys       Date:  2008-04-18       Impact factor: 7.038

10.  Phase II study of pre-irradiation chemotherapy for childhood intracranial ependymoma. Children's Cancer Group protocol 9942: a report from the Children's Oncology Group.

Authors:  James H Garvin; Michael T Selch; Emi Holmes; Mitchell S Berger; Jonathan L Finlay; Ann Flannery; Joel W Goldwein; Roger J Packer; Lucy B Rorke-Adams; Tania Shiminski-Maher; Richard Sposto; Philip Stanley; Raymond Tannous; Ian F Pollack
Journal:  Pediatr Blood Cancer       Date:  2012-09-04       Impact factor: 3.167

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  14 in total

Review 1.  Pediatric Brain Tumors: Current Knowledge and Therapeutic Opportunities.

Authors:  John Glod; Gilbert J Rahme; Harpreet Kaur; Eric H Raabe; Eugene I Hwang; Mark A Israel
Journal:  J Pediatr Hematol Oncol       Date:  2016-05       Impact factor: 1.289

2.  Extent of re-excision, sequence/timing of salvage re-irradiation, and disease-free interval impact upon clinical outcomes in recurrent/progressive ependymoma.

Authors:  Tejpal Gupta; Madan Maitre; Priyamvada Gupta; Rahul Krishnatry; Abhishek Chatterjee; Aliasgar Moiyadi; Prakash Shetty; Vikas Singh; Girish Chinnaswamy; Sridhar Epari; Ayushi Sahay; Vijay Patil; Jayant GodaSastri
Journal:  J Neurooncol       Date:  2020-02-18       Impact factor: 4.130

Review 3.  Current and Emerging Methods of Management of Ependymoma.

Authors:  Sebastian M Toescu; Kristian Aquilina
Journal:  Curr Oncol Rep       Date:  2019-07-29       Impact factor: 5.075

4.  Re-irradiation of recurrent anaplastic ependymoma using radiosurgery or fractionated stereotactic radiotherapy.

Authors:  Taro Murai; Kengo Sato; Michio Iwabuchi; Yoshihiko Manabe; Hiroyuki Ogino; Hiromitsu Iwata; Koshi Tatewaki; Naoki Yokota; Seiji Ohta; Yuta Shibamoto
Journal:  Jpn J Radiol       Date:  2015-12-18       Impact factor: 2.374

5.  Short Hypofractionated Radiation Therapy in Palliation of Pediatric Malignancies: Outcomes and Toxicities.

Authors:  Stanislav Lazarev; Brian H Kushner; Suzanne L Wolden
Journal:  Int J Radiat Oncol Biol Phys       Date:  2018-08-02       Impact factor: 7.038

6.  Craniospinal irradiation as part of re-irradiation for children with recurrent intracranial ependymoma.

Authors:  Derek S Tsang; Louise Murray; Vijay Ramaswamy; Michal Zapotocky; Uri Tabori; Ute Bartels; Annie Huang; Peter B Dirks; Michael D Taylor; Cynthia Hawkins; Eric Bouffet; Normand Laperriere
Journal:  Neuro Oncol       Date:  2019-03-18       Impact factor: 12.300

7.  Final results of the second prospective AIEOP protocol for pediatric intracranial ependymoma.

Authors:  Maura Massimino; Rosalba Miceli; Felice Giangaspero; Luna Boschetti; Piergiorgio Modena; Manila Antonelli; Paolo Ferroli; Daniele Bertin; Emilia Pecori; Laura Valentini; Veronica Biassoni; Maria Luisa Garrè; Elisabetta Schiavello; Iacopo Sardi; Armando Cama; Elisabetta Viscardi; Giovanni Scarzello; Silvia Scoccianti; Maurizio Mascarin; Lucia Quaglietta; Giuseppe Cinalli; Barbara Diletto; Lorenzo Genitori; Paola Peretta; Anna Mussano; Annamaria Buccoliero; Giuseppina Calareso; Salvina Barra; Angela Mastronuzzi; Carlo Giussani; Carlo Efisio Marras; Rita Balter; Patrizia Bertolini; Ermanno Giombelli; Milena La Spina; Francesca R Buttarelli; Bianca Pollo; Lorenza Gandola
Journal:  Neuro Oncol       Date:  2016-05-18       Impact factor: 12.300

Review 8.  EANO guidelines for the diagnosis and treatment of ependymal tumors.

Authors:  Roberta Rudà; Guido Reifenberger; Didier Frappaz; Stefan M Pfister; Anne Laprie; Thomas Santarius; Patrick Roth; Joerg Christian Tonn; Riccardo Soffietti; Michael Weller; Elizabeth Cohen-Jonathan Moyal
Journal:  Neuro Oncol       Date:  2018-03-27       Impact factor: 12.300

9.  Acute and chronic hemorrhage from radiation-induced cavernous malformation associated with late-delayed radiation necrosis in long surviving glioma patients: A case report.

Authors:  Tomoya Oishi; Tomohiro Yamasaki; Satoshi Baba; Shinichiro Koizumi; Tetsuro Sameshima; Hiroki Namba
Journal:  Oncol Lett       Date:  2019-11-19       Impact factor: 2.967

10.  Molecular sub-group-specific immunophenotypic changes are associated with outcome in recurrent posterior fossa ependymoma.

Authors:  Lindsey M Hoffman; Andrew M Donson; Ichiro Nakachi; Andrea M Griesinger; Diane K Birks; Vladimir Amani; Molly S Hemenway; Arthur K Liu; Michael Wang; Todd C Hankinson; Michael H Handler; Nicholas K Foreman
Journal:  Acta Neuropathol       Date:  2013-11-17       Impact factor: 17.088

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