Literature DB >> 24077994

Can we regrow a human arm? A negative perspective from an upper-limb surgeon.

Antonio Merolli.   

Abstract

If we would like to devote time and money to the task of regrowing a human arm, we should feel free to do it, in principle. However, if we recognize a purpose in biomedical research, we must scrutinize this task in the light of a possible clinical application. We will then discover that regrowing a human arm is not only likely to be not possible, but also not required in the clinic. Bionic arms and better reconstructive surgery already provide a different, simpler and easier solution to the loss of a human arm, and should be promoted. Probably, ‘‘can we regrow a human arm?’’ is not the right question. Instead, we should ask, ‘‘can we restore the function of a lost human arm?’’.

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Year:  2013        PMID: 24077994     DOI: 10.1007/s10856-013-5045-8

Source DB:  PubMed          Journal:  J Mater Sci Mater Med        ISSN: 0957-4530            Impact factor:   3.896


  10 in total

Review 1.  Control of muscle fibre and motoneuron diversification.

Authors:  S M Hughes; P C Salinas
Journal:  Curr Opin Neurobiol       Date:  1999-02       Impact factor: 6.627

Review 2.  Bionic prosthetic hands: A review of present technology and future aspirations.

Authors:  R G E Clement; K E Bugler; C W Oliver
Journal:  Surgeon       Date:  2011-07-13       Impact factor: 2.392

Review 3.  Ethical, financial, and policy considerations in hand transplantation.

Authors:  Jeff Chang; David W Mathes
Journal:  Hand Clin       Date:  2011-09-21       Impact factor: 1.907

4.  Prosthesis use in adult acquired major upper-limb amputees: patterns of wear, prosthetic skills and the actual use of prostheses in activities of daily life.

Authors:  Kristin Østlie; Ingrid Marie Lesjø; Rosemary Joy Franklin; Beate Garfelt; Ola Hunsbeth Skjeldal; Per Magnus
Journal:  Disabil Rehabil Assist Technol       Date:  2012-02-09

Review 5.  What mechanisms control neoteny and regulate induced metamorphosis in urodeles?

Authors:  P Rosenkilde; A P Ussing
Journal:  Int J Dev Biol       Date:  1996-08       Impact factor: 2.203

Review 6.  Quality of life considerations in upper limb transplantation: review and future directions.

Authors:  Sally E Jensen; Zeeshan Butt; Alex Bill; Talia Baker; Michael M Abecassis; Allen W Heinemann; David Cella; Gregory A Dumanian
Journal:  J Hand Surg Am       Date:  2012-08-30       Impact factor: 2.230

7.  The role of mechanical loading histories in the development of diarthrodial joints.

Authors:  D R Carter; M Wong
Journal:  J Orthop Res       Date:  1988       Impact factor: 3.494

Review 8.  Nerve growth factor signaling, neuroprotection, and neural repair.

Authors:  M V Sofroniew; C L Howe; W C Mobley
Journal:  Annu Rev Neurosci       Date:  2001       Impact factor: 12.449

9.  Induction of nerve growth factor receptor in Schwann cells after axotomy.

Authors:  M Taniuchi; H B Clark; E M Johnson
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

Review 10.  Making digit patterns in the vertebrate limb.

Authors:  Cheryll Tickle
Journal:  Nat Rev Mol Cell Biol       Date:  2006-01       Impact factor: 94.444

  10 in total
  1 in total

Review 1.  Regeneration and repair of human digits and limbs: fact and fiction.

Authors:  Shyh-Jou Shieh; Tsun-Chih Cheng
Journal:  Regeneration (Oxf)       Date:  2015-10-13
  1 in total

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