Literature DB >> 24077212

False positive radiographical evidence of pump catheter migration into the spinal cord.

Simon Dardashti1, Eric Y Chang, Robert B Kim, Kais I Alsharif, Justin T Hata, Danielle M Perret.   

Abstract

Intrathecal drug delivery systems are becoming an increasingly common modality used by physicians to treat patients. Specifically, chronic spasticity secondary to multiple sclerosis (MS) may be treated with intrathecal baclofen (ITB) therapy when oral antispasmodics do not provide adequate relief. ITB therapy is effective, localizes drug delivery, and does not have the same degree of intolerable systemic effects often seen with oral and parenteral medications. As the use of intrathecal drug delivery systems has become more common, so has the incidence of adverse events. ITB administration requires the surgical implantation of indwelling catheters and a pump reservoir. Although this therapy is useful in treating spasticity, risks unique to intrathecal drug delivery systems include medication dosing errors, pump malfunction, infection, and catheter breakage or dislocation. To our knowledge intrathecal pump catheter migration into the spinal cord is a very rare complication with only 2 such complications reported. We present a case of an intrathecal baclofen pump catheter that was initially believed to have migrated into the spinal cord and the innovative use of cinefluoroscopy and digital subtraction used to identify catheter placement. Moreover, after confirmation of the catheter position within the spinal cord on magnetic resonance imaging (MRI) our team elected to perform a laminectomy, which demonstrated that the catheter was not in the spinal cord but was surrounded by arachnoid adhesions. We hope our efforts will provide the clinician insight into the common difficulties that arise and how best to troubleshoot them to serve this specific patient population and prevent potentially life-threatening complications.

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Year:  2013        PMID: 24077212      PMCID: PMC4349418     

Source DB:  PubMed          Journal:  Pain Physician        ISSN: 1533-3159            Impact factor:   4.965


  10 in total

Review 1.  Imaging evaluation of intrathecal baclofen pump-catheter systems.

Authors:  A C Miracle; M A Fox; R N Ayyangar; A Vyas; S K Mukherji; D J Quint
Journal:  AJNR Am J Neuroradiol       Date:  2010-10-28       Impact factor: 3.825

2.  Intraparenchymal migration of an intrathecal catheter three years after implantation.

Authors:  Eric Albrecht; Anne Durrer; Dominique Chédel; Philippe Maeder; Eric Buchser
Journal:  Pain       Date:  2005-09-30       Impact factor: 6.961

Review 3.  Intrathecal baclofen in multiple sclerosis: too little, too late?

Authors:  April Erwin; Mark Gudesblatt; Francois Bethoux; Susan E Bennett; Stephen Koelbel; Robert Plunkett; Saud Sadiq; Valerie L Stevenson; Ann-Marie Thomas; Carlo Tornatore; Mauro Zaffaroni; Mary Hughes
Journal:  Mult Scler       Date:  2011-01-31       Impact factor: 6.312

4.  Treatment of spasticity related to multiple sclerosis with intrathecal baclofen: a long-term follow-up.

Authors:  Tiina Rekand; Marit Grønning
Journal:  J Rehabil Med       Date:  2011-05       Impact factor: 2.912

5.  Traumatic syrinx after implantation of an intrathecal catheter.

Authors:  Donal Harney; Raymond Victor
Journal:  Reg Anesth Pain Med       Date:  2004 Nov-Dec       Impact factor: 6.288

6.  A prospective study of catheter-related complications of intrathecal drug delivery systems.

Authors:  K A Follett; C P Naumann
Journal:  J Pain Symptom Manage       Date:  2000-03       Impact factor: 3.612

Review 7.  Spasticity treatment with botulinum toxins.

Authors:  A B Ward
Journal:  J Neural Transm (Vienna)       Date:  2008-04-04       Impact factor: 3.575

8.  Prevalence and treatment of spasticity reported by multiple sclerosis patients.

Authors:  M A Rizzo; O C Hadjimichael; J Preiningerova; T L Vollmer
Journal:  Mult Scler       Date:  2004-10       Impact factor: 6.312

9.  Excitatory amino acids and multiple sclerosis: evidence from cerebrospinal fluid.

Authors:  Paola Sarchielli; Laura Greco; Ardesio Floridi; Alessandro Floridi; Virgilio Gallai
Journal:  Arch Neurol       Date:  2003-08

10.  Intrathecal baclofen for stiff-person syndrome: life-threatening intermittent catheter leakage.

Authors:  J Bardutzky; V Tronnier; S Schwab; H-M Meinck
Journal:  Neurology       Date:  2003-06-24       Impact factor: 9.910

  10 in total
  2 in total

Review 1.  The leptomeninges as a critical organ for normal CNS development and function: First patient and public involved systematic review of arachnoiditis (chronic meningitis).

Authors:  Carol S Palackdkharry; Stephanie Wottrich; Erin Dienes; Mohamad Bydon; Michael P Steinmetz; Vincent C Traynelis
Journal:  PLoS One       Date:  2022-09-30       Impact factor: 3.752

2.  Plain radiography in patients treated with intrathecal drug delivery using an implantable pump device.

Authors:  Elmar M Delhaas; Biswadjiet S Harhangi; Sander P G Frankema; Frank J P M Huygen; Aad van der Lugt
Journal:  Insights Imaging       Date:  2017-08-24
  2 in total

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