| Literature DB >> 24073790 |
Xiaoyu Ren1, Ping Wen, Xiaokang Shi, Yuling Wang, Jian Li, Sizhuo Yang, Hao Yan, Guosheng Huang.
Abstract
An efficient method for the Pd-catalyzed regioselective C-2 arylation of quinolines is presented. Reactions of various substituted quinolines and unactivated arenes have been conducted under mild conditions. The result shows good product yields of 2-arylquinolines, which are highly useful building blocks for the synthesis of bioactive alkaloid natural products and drug molecules.Entities:
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Year: 2013 PMID： 24073790 DOI： 10.1021/ol402262c
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005