Literature DB >> 24071493

Interventional oncology in the elderly: complications and early response in liver and kidney malignancies.

L Monfardini1, P Della Vigna, G Bonomo, F Orsi, M Tullii, D Disalvatore, S Monfardini.   

Abstract

OBJECTIVES: The complication rate, loco-regional responses and length of hospital stay were analyzed in patients with liver and kidney cancer older than 70years treated with interventional oncology procedures. The findings from the older population were compared with the younger patients (<70years) to detect any difference not related to chance.
MATERIALS AND METHODS: Prospectively collected data on patients who underwent hepatic artery embolization (with or without radiofrequency ablation) and kidney radiofrequency ablation were retrospectively analyzed. Complication rates, loco-regional responses and length of hospital stay for patients older and younger than 70 were compared.
RESULTS: 163 patients were treated, 66 (40.5%) older and 97 (59.5%) younger than 70years. The complication rate in patients older than 70 was 4.5% (3/66 pts) versus 3.1% (3/97 pts) (p=0.69) in the younger age-group. The complication rates for the liver embolization group, liver embolization plus radiofrequency and kidney radiofrequency group were 2/90 pts (2.2%), 2/42 pts (4.8%) and 2/31 pts (6.5%), respectively (p=0.46). Median hospital stay was three nights in both older and younger patients. Response rates were not significantly influenced by age.
CONCLUSION: Liver embolization with or without radiofrequency and renal radiofrequency are safe and effective in older patients. Age alone should not be considered a contraindication to treatment in carefully selected patients.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 24071493     DOI: 10.1016/j.jgo.2012.09.001

Source DB:  PubMed          Journal:  J Geriatr Oncol        ISSN: 1879-4068            Impact factor:   3.599


  1 in total

1.  Impact of liver-directed therapy in colorectal cancer liver metastases.

Authors:  Gabriela M Vargas; Abhishek D Parmar; Kristin M Sheffield; Nina P Tamirisa; Kimberly M Brown; Taylor S Riall
Journal:  J Surg Res       Date:  2014-06-04       Impact factor: 2.192

  1 in total

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