Literature DB >> 24070847

Reduced susceptibility of Candida albicans clinical isolates to azoles and detection of mutations in the ERG11 gene.

Lei Zhang1, Hai-Fei Yang, Yan-Yan Liu, Xi-Hai Xu, Ying Ye, Jia-Bin Li.   

Abstract

We investigated the susceptibility of Candida albicans isolated from clinic specimens to azole antifungal agents and estimated the association of the ERG11 mutations with azole resistance during recent 5years in China. In this study, novel mutations G346A, A434V, and L480F in ERG11 may be related to azole resistance in C. albicans.
© 2013.

Entities:  

Keywords:  Azoles; Candidiasis; Drug resistance; MICs

Mesh:

Substances:

Year:  2013        PMID: 24070847     DOI: 10.1016/j.diagmicrobio.2013.08.018

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN: 0732-8893            Impact factor:   2.803


  3 in total

Review 1.  Molecular and genetic basis of azole antifungal resistance in the opportunistic pathogenic fungus Candida albicans.

Authors:  Andrew T Nishimoto; Cheshta Sharma; P David Rogers
Journal:  J Antimicrob Chemother       Date:  2020-02-01       Impact factor: 5.790

2.  Identification and antifungal susceptibility of Candida species isolated from bloodstream infections in Konya, Turkey.

Authors:  Hatice Turk Dagi; Duygu Findik; Cigdem Senkeles; Ugur Arslan
Journal:  Ann Clin Microbiol Antimicrob       Date:  2016-05-31       Impact factor: 3.944

Review 3.  Distribution and antifungal susceptibility pattern of Candida species from mainland China: A systematic analysis.

Authors:  Hazrat Bilal; Muhammad Shafiq; Bing Hou; Rehmat Islam; Muhammad Nadeem Khan; Rahat Ullah Khan; Yuebin Zeng
Journal:  Virulence       Date:  2022-12       Impact factor: 5.428

  3 in total

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