Regina Promberger1, Michael Hermann2, Shanon Joan Pallikunnel2, Rudolf Seemann3, Moritz Meusel2, Johannes Ott4. 1. Second Department of Surgery "Kaiserin Elisabeth", Krankenanstalt Rudolfstiftung, Vienna, Austria; Department of Surgery, Medical University of Vienna, Vienna, Austria. 2. Second Department of Surgery "Kaiserin Elisabeth", Krankenanstalt Rudolfstiftung, Vienna, Austria. 3. Second Department of Surgery "Kaiserin Elisabeth", Krankenanstalt Rudolfstiftung, Vienna, Austria; Department of Craniomaxillofacial and Oral Surgery, Medical University of Vienna, Vienna, Austria. 4. Second Department of Surgery "Kaiserin Elisabeth", Krankenanstalt Rudolfstiftung, Vienna, Austria; Department of Gynecologic Endocrinology and Reproductive Medicine, Medical University Vienna, Waehringer Guertel 18-20, 1090 Vienna, Austria. Electronic address: johannes.ott@meduniwien.ac.at.
Abstract
BACKGROUND: Hashimoto's thyroiditis is associated with decreased quality of life (QoL). Thyroid surgery could hypothetically lead to an increase in QoL. METHODS: In a follow-up analysis of a prospective cohort study that included euthyroid women undergoing thyroid surgery for benign thyroid disease, 248 patients were willing to answer the SF-36 QoL questionnaire. RESULTS: At follow-up after a median of 26 months, only the SF-36 module of "bodily pain" had increased (P = .046). Preoperative anti-thyroid peroxidase antibody levels were positively correlated with increasing QoL in the SF-36 modules "bodily pain" (P < .001) and "role emotional" (P < .001). For the presence of histologically confirmed Hashimoto's thyroiditis, a significant positive correlation (P < .001) was found for all modules apart from "physical functioning." CONCLUSIONS: In women with benign euthyroid goiter, thyroid surgery does not lead to an overall improvement in health-related QoL. It should not be recommended for patients with elevated anti-thyroid peroxidase antibody levels. Patients with histologically confirmed Hashimoto's thyroiditis might benefit in terms of QoL.
BACKGROUND:Hashimoto's thyroiditis is associated with decreased quality of life (QoL). Thyroid surgery could hypothetically lead to an increase in QoL. METHODS: In a follow-up analysis of a prospective cohort study that included euthyroid women undergoing thyroid surgery for benign thyroid disease, 248 patients were willing to answer the SF-36 QoL questionnaire. RESULTS: At follow-up after a median of 26 months, only the SF-36 module of "bodily pain" had increased (P = .046). Preoperative anti-thyroid peroxidase antibody levels were positively correlated with increasing QoL in the SF-36 modules "bodily pain" (P < .001) and "role emotional" (P < .001). For the presence of histologically confirmed Hashimoto's thyroiditis, a significant positive correlation (P < .001) was found for all modules apart from "physical functioning." CONCLUSIONS: In women with benign euthyroid goiter, thyroid surgery does not lead to an overall improvement in health-related QoL. It should not be recommended for patients with elevated anti-thyroid peroxidase antibody levels. Patients with histologically confirmed Hashimoto's thyroiditis might benefit in terms of QoL.
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