Literature DB >> 24070479

Liquid chromatography coupled to on-line post column derivatization for the determination of organic compounds: a review on instrumentation and chemistries.

Constantinos K Zacharis1, Paraskevas D Tzanavaras.   

Abstract

Analytical derivatization either in pre or post column modes is one of the most widely used sample pretreatment techniques coupled to liquid chromatography. In the present review article we selected to discuss the post column derivatization mode for the analysis of organic compounds. The first part of the review focuses to the instrumentation of post-column setups including not only fundamental components such as pumps and reactors but also less common parts such as static mixers and back-pressure regulators; the second part of the article discusses the most popular "chemistries" that are involved in post column applications, including reagent-less approaches and new sensing platforms such as the popular gold nanoparticles. Some representative recent applications are also presented as tables.
Copyright © 2013 Elsevier B.V. All rights reserved.

Keywords:  1,2-naphthoquinone-4-sulfonate; 2,2-diphenyl-1-picrylhydrazyl; 2,2′-azinobis-(3-ehtylbenzothiazoline-6-sulphonate; 2,3-naphthalenedicarboxaldehyde; 5,5′-dithiobis-(2-nitrobenzoic acid; 7-chloro-4-nitro-2,1,3-benzoxadiazole; ABTS; ADA; AuNPs; CL; DMAB; DPPH; DTNB; Determination; ECL; FEP; FRET; HPLC; KOT; LC; Liquid chromatography; NBD-Cl; NDA; NPs; NQS; OPA; OT; Organic compounds; PBPB; PCD; PEEK; PTFE; PVC; Post-column derivatization; RF-HPLC; Review; Ru(bpy)(3)(2+); SET; TNB; UV; anthracene-2,3-dicarboxaldehyde; chemiluminescence; dimethylaminobenzaldehyde; electrochemiluminescence; florinated ethylene propylene; fluorescence resonance energy transfer; gold nanoparticles; high pressure liquid chromatography; knitted open tubular; liquid chromatography; nanoparticles; o-phthalaldehyde; open tubular; polyetheretherketone; polytetrafluoroethylene (Teflon); polyvinyl chloride; post-column derivatization; pyridinium hydrobromide perbromide; reaction flow chromatography; single electron transfer; thiol-5-thio-2-nitrobenzoic acid; tris(2,2′-bipyridine)rythenium (III); ultraviolet

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Year:  2013        PMID: 24070479     DOI: 10.1016/j.aca.2013.07.032

Source DB:  PubMed          Journal:  Anal Chim Acta        ISSN: 0003-2670            Impact factor:   6.558


  5 in total

1.  Post Column Derivatization Using Reaction Flow High Performance Liquid Chromatography Columns.

Authors:  Andrew Jones; Sercan Pravadali-Cekic; Stanley Hua; Danijela Kocic; Michelle Camenzuli; Gary Dennis; Andrew Shalliker
Journal:  J Vis Exp       Date:  2016-04-26       Impact factor: 1.355

2.  HPLC method with post-column derivatization for the analysis of endogenous histidine in human saliva validated using the total-error concept.

Authors:  Anna-Maria Gkantiri; Apostolia Tsiasioti; Constantinos K Zacharis; Paraskevas D Tzanavaras
Journal:  Amino Acids       Date:  2022-02-19       Impact factor: 3.520

3.  HPLC Determination of Colistin in Human Urine Using Alkaline Mobile Phase Combined with Post-Column Derivatization: Validation Using Accuracy Profiles.

Authors:  Kalliopi Papavasileiou; Apostolia Tsiasioti; Paraskevas D Tzanavaras; Constantinos K Zacharis
Journal:  Molecules       Date:  2022-05-28       Impact factor: 4.927

4.  Automated Stopped-Flow Fluorimetric Sensor for Biologically Active Adamantane Derivatives Based on Zone Fluidics.

Authors:  Paraskevas D Tzanavaras; Sofia Papadimitriou; Constantinos K Zacharis
Journal:  Molecules       Date:  2019-11-03       Impact factor: 4.411

5.  HPLC-CUPRAC post-column derivatization method for the determination of antioxidants: a performance comparison between porous silica and core-shell column packing.

Authors:  Syed A Haque; Socrates Jose P Cañete
Journal:  J Anal Sci Technol       Date:  2018-01-17
  5 in total

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