Literature DB >> 2407031

Mohs' micrographic surgery of the head and neck.

G L Darmstadt1, H K Steinman.   

Abstract

Mohs' micrographic surgery, a method originally developed in the 1930s to remove contiguously spreading cutaneous cancers under precise microscopic control, has emerged as the most reliable method for removing certain primary, incompletely excised, and recurrent basal cell and squamous cell carcinomas. Indications for its use have expanded to include many other cutaneous and noncutaneous neoplasms. Usually done as an outpatient procedure and using local anesthesia, a layer of tissue is excised, mapped in relation to the site of removal, sectioned horizontally, and examined for the presence of residual tumor. This sequence is repeated, removing only tissue that contains residual tumor, until a margin completely free of cancer is reached. Extremely high cure rates are achieved, and surrounding tissue is maximally conserved for wound repair.

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Year:  1990        PMID: 2407031      PMCID: PMC1002291     

Source DB:  PubMed          Journal:  West J Med        ISSN: 0093-0415


  33 in total

1.  Chemosurgery in the treatment of cancer.

Authors:  G R Mikhail
Journal:  Int J Dermatol       Date:  1975 Jan-Feb       Impact factor: 2.736

2.  Histopathologic considerations in the management of skin cancer.

Authors:  R G Freeman
Journal:  J Dermatol Surg       Date:  1976-06

3.  Microscopically controlled excision of skin tumors.

Authors:  T A Tromovitch; S J Stegeman
Journal:  Arch Dermatol       Date:  1974-08

4.  Treatment of basal cell carcinoma of the head and neck.

Authors:  P Thomas
Journal:  Rev Surg       Date:  1970 Jul-Aug

5.  Significance of marginal extension in excised basal-cell carcinoma.

Authors:  C A Gooding; G White; M Yatsuhashi
Journal:  N Engl J Med       Date:  1965-10-21       Impact factor: 91.245

6.  The recurrent basal cell epithelioma. A study of 100 cases of recurrent, re-treated basal cell epitheliomas.

Authors:  H Menn; P Robins; A W Kopf; R S Bart
Journal:  Arch Dermatol       Date:  1971-06

7.  Incurable recurrences of basal cell carcinoma of the mid-face following radiation therapy.

Authors:  B Hirshowitz; D Mahler
Journal:  Br J Plast Surg       Date:  1971-04

8.  Chemosurgery: microscopically controlled surgery for skin cancer--past, present and future.

Authors:  F E Mohs
Journal:  J Dermatol Surg Oncol       Date:  1978-01

9.  The value of typing basal cell carcinomas in predicting recurrence after surgical excision.

Authors:  J P Sloane
Journal:  Br J Dermatol       Date:  1977-02       Impact factor: 9.302

10.  Chemosurgery for melanoma.

Authors:  F E Mohs
Journal:  Arch Dermatol       Date:  1977-03
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  2 in total

1.  More on Mohs'.

Authors:  H K Steinman
Journal:  West J Med       Date:  1990-12

2.  A pathologist's view of Mohs' micrographic surgery.

Authors:  R E Safrin
Journal:  West J Med       Date:  1990-06
  2 in total

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