| Literature DB >> 24069172 |
Shunichi Fukuhara1, Takafumi Wakita, Masakazu Yamada, Yoshimune Hiratsuka, Joseph Green, Kotaro Oki.
Abstract
PURPOSE: In clinical ophthalmology as in other fields, measuring patient-reported outcomes imposes a burden on patients. To decrease that burden, we used item-response theory (IRT) to develop and test a short version of the National Eye Institute's Visual Function Questionnaire (VFQ).Entities:
Mesh:
Year: 2013 PMID: 24069172 PMCID: PMC3771973 DOI: 10.1371/journal.pone.0073084
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Estimates of item parameters.
| Item number | Domain | Factor loading | Slope | Location | Model fit | Missing (%) |
| 2 | General vision | .738 | 0.858 | 0.168 | 0.952 | 0.7 |
| 3 | Well-being, distress | .828 | 0.752 | 0.093 | 0.068 | 0.4 |
| 5 | Near vision | .863 | 1.066 | −0.153 | 0.021 | 5.8 |
| 6 | Near vision | .760 | 0.839 | −0.125 | 0.204 | 13.0 |
| 7 | Near vision | .815 | 1.265 | −0.380 | 0.011 | 28.3 |
| 8 | Distance vision | .837 | 0.904 | −0.365 | 0.405 | 4.0 |
| 9 | Distance vision | .745 | 0.642 | −0.018 | 0.445 | 8.7 |
| 11 | Social functioning | .767 | 1.066 | −0.677 | 0.115 | 14.5 |
| 13 | Social functioning | .708 | 0.931 | −0.841 | 0.109 | 9.1 |
| 14 | Distance vision | .868 | 1.643 | −0.112 | 0.112 | 31.9 |
| 17 | Role limitation | .928 | 1.056 | −0.711 | 0.110 | 0.4 |
| 18 | Role limitation | .860 | 0.715 | −0.797 | 0.003 | 1.1 |
| 20 | Dependency | .844 | 1.024 | −0.865 | 0.000 | 0.4 |
| 21 | Well-being, distress | .693 | 0.674 | −0.836 | 0.000 | 0.4 |
| 22 | Well-being, distress | .873 | 1.266 | −0.331 | 0.004 | 0.7 |
| 23 | Dependency | .766 | 0.878 | −1.026 | 0.001 | 0.0 |
| 24 | Dependency | .847 | 1.338 | −0.904 | 0.000 | 0.0 |
| 25 | Well-being, distress | .725 | 0.849 | −0.822 | 0.015 | 0.4 |
|
| General vision | .891 | 0.531 | −0.371 | 0.039 | 5.8 |
|
| Near vision | .897 | 1.111 | 0.084 | 0.138 | 2.2 |
|
| Near vision | .909 | 1.612 | −0.285 | 0.509 | 12.3 |
|
| Near vision | .282 | 0.285 | −2.196 | 0.014 | 1.1 |
|
| Distance vision | .779 | 0.863 | −0.431 | 0.397 | 6.9 |
|
| Distance vision | .588 | 0.366 | −0.593 | 0.016 | 38.4 |
|
| Distance vision | .758 | 1.137 | −0.670 | 0.344 | 1.8 |
|
| Social functioning | .413 | 0.719 | −1.884 | 0.000 | 5.8 |
|
| Role limitation | .597 | 0.836 | −1.226 | 0.057 | 0.4 |
|
| Role limitation | .776 | 0.983 | −0.951 | 0.001 | 1.1 |
|
| Well-being, distress | .791 | 0.653 | −0.780 | 0.000 | 0.0 |
|
| Dependency | .422 | 0.432 | −1.616 | 0.230 | 0.0 |
| Deleted items | ||||||
| 1 | General health | .208 | 0.4 | |||
| 4 | Ocular pain | .059 | 0.4 | |||
| 10 | Peripheral vision | .142 | 2.2 | |||
| 12 | Color vision | .395 | 9.8 | |||
| 19 | Ocular pain | .189 | 0.0 | |||
|
| General health | .265 | 2.9 |
*: optional items.
**: p value from χ2 test.
Candidate items, and the 11 items chosen (*) for the short version of the VFQ (the VFQ-J11).
| Domain | Number of items | Item numbers |
| General vision | 1 | 2* |
| Near vision | 4 | 5*, 6*, optional-3*, optional-4 |
| Distance vision | 3 | 8*, optional-6*, optional-8* |
| Dependency | 3 | 20, 23, 24* |
| Social functioning | 2 | 11*, 13 |
| Well-being, distress | 2 | 22, 25* |
| Role limitation | 3 | 17*, optional-11A, optional-11B |
See Table 1 for item numbers.
VFQ: The Visual Function Questionnaire originally developed by the National Eye Institute.
VFQ-J11: The short-form VFQ 11-item Japanese version.
Figure 1Targeting of item thresholds with regard to the patients in this study.
The Figure shows locations of the patients (above) and of the item thresholds (below) on the same scale, in units of the latent trait.
Figure 2Test information functions for the VFQ25 and the VFQ-J11.
Both functions reached their maxima at about the same value of the latent trait (a theta of approximately −0.8). For values of theta between approximately −2.0 and +0.8, the test information for the VFQ-J11 was greater than 9, which indicates that in that range (−2.0 to +0.8) the test's reliability is equivalent to or greater than a Cronbach's alpha of 0.9.
Scores on the VFQ25 and VFQ-J11 in patients with different eye diseases.
| Eye disease | VFQ25 | VFQ-J11 | |
| n | Mean ± SD | Mean ± SD | |
| 1. None | 31 | 86.51±9.51 | 88.79±10.21 |
| 2. Glaucoma | 69 | 72.33±17.35 | 73.63±19.07 |
| 3. Cataract | 96 | 66.29±16.32 | 64.85±17.20 |
| 4. Age-related macular degeneration | 80 | 48.75±21.70 | 43.02±24.92 |
| All groups | 276 | 64.99±21.32 | 63.41±24.54 |
Results of one-way ANOVA among the four diagnosis groups were as follows: F(2, 272) = 41.61 for the VFQ25, and 52.35 for the VFQ-J11. Post-hoc tests by Tukey's method resulted in p values less than 0.05 for all comparisons except one: the comparison of VFQ25 results between group 2 and group 3.
VFQ25: The 25-item Visual Function Questionnaire originally developed by the National Eye Institute.
VFQ-J11: The short-form VFQ 11-item Japanese version.
Correlations of scores on the VFQ25 and the VFQ-J11 with visual acuity and with visual field.
| n | VFQ25 | VFQ-J11 | ||
| Better eye | 0.669 | 0.719 | ||
| Visual acuity | 271 | |||
| Worse eye | 0.611 | 0.659 | ||
| Better eye | 0.498 | 0.513 | ||
| Field of vision | 63 | |||
| Worse eye | 0.391 | 0.417 |
VFQ25: The 25-item Visual Function Questionnaire originally developed by the National Eye Institute.
VFQ-J11: The short-form VFQ 11-item Japanese version.