| Literature DB >> 2406894 |
Abstract
A range of cytokines have been suggested as intermediaries which may have effects on cellular metabolism and proliferation. Interleukin 1 has been most intensively studied and has multiple biological activities, however other polypeptides may also have significant effects on cartilage. A greater understanding of the biochemical mechanisms involved in the development and progression of osteoarthritis (OA) may lead to a rational approach to therapeutic management.Entities:
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Year: 1990 PMID： 2406894 DOI： 10.3109/03009749009096939
Source DB: PubMed Journal: Scand J Rheumatol Suppl ISSN： 0301-3847