| Literature DB >> 24065627 |
Ercan Varol1, Fatih Aksoy2, Hasan Aydin Bas2, Hatem Ari2, Mehmet Ozaydin2.
Abstract
A low high-density lipoprotein cholesterol (HDL-C) level is a predictor of increased cardiovascular risk. We assessed the mean platelet volume (MPV) in patients with low HDL-C. We studied 59 patients with low HDL-C (HDL-C ≤35 mg/dL) and 56 control participants (HDL-C levels >35 mg/dL) with similar cardiovascular risk factors. As expected, HDL-C was significantly lower among the patients with low HDL-C than that of the control group (32 ± 3 vs 51 ± 5 mg/dL, respectively; P < .001). Platelet count was significantly lower among the patients with low HDL-C than that of the control group (213 ± 60 vs 285 ± 75 × 10(9)/L, respectively; P < .001). The MPV was significantly higher among the patients with low HDL-C than that of the control group (8.7 ± 0.6 vs 7.1 ± 0.5 fL, respectively; P < .001). We have shown that MPV was significantly elevated in patients with low HDL-C compared with control participants.Entities:
Keywords: high-density lipoprotein cholesterol; mean platelet volume; platelet activation
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Year: 2013 PMID： 24065627 DOI： 10.1177/0003319713504024
Source DB: PubMed Journal: Angiology ISSN： 0003-3197 Impact factor: 3.619