| Literature DB >> 24064196 |
Megan Ratterman1, Kimberly Kruczek1, Suela Sulo2, Tait D Shanafelt3, Neil E Kay3, Chadi Nabhan4.
Abstract
The prognostic significance of extra-medullary chronic lymphocytic leukemia (EM-CLL) is unknown. We conducted a Medline database systematic search analyzing English language articles published between 1975 and 2012 identifying 192 cases. Patients with EM-CLL were more commonly treated than not (p < .001). Skin and central nervous system (CNS) were the most commonly reported sites of organ involvement. Survival after diagnosis of EM-CLL appeared to depend on the site of EM involvement. Prospective evaluation and further studies of EM-CLL are warranted.Entities:
Keywords: CLL; Chronic lymphocytic leukemia; Extra-medullary; Prognosis
Mesh:
Year: 2013 PMID: 24064196 DOI: 10.1016/j.leukres.2013.08.009
Source DB: PubMed Journal: Leuk Res ISSN: 0145-2126 Impact factor: 3.156