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Literature DB >> 2406145

Immunological features of diffuse connective tissue diseases.

Abstract

Diffuse connective tissue diseases (DCTD) represent an heterogeneous group of disorders characterized by systemic inflammatory reactions that are currently classified on clinical grounds. Their aetiopathogenesis is largely unknown and appears to be very complex, associating exogenous factors with an immunogenetic predisposition. In the last decade, studies on human leukocyte antigen (HLA)-disease associations and antinuclear antibodies have provided some useful clues for the diagnosis and clinical management of DCTD.

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Year: 1990 PMID： 2406145 DOI： 10.1007/bf02106277

Source DB: PubMed Journal: Eur J Pediatr ISSN： 0340-6199 Impact factor: 3.183

45 in total

Immunological features of diffuse connective tissue diseases.

Review 1. The basis for the immunoregulatory role of macrophages and other accessory cells.

2. Identification of antihistone antibodies in subsets of juvenile chronic arthritis.

3. Juvenile progressive systemic sclerosis: clinical and serologic findings.

Review 4. Murine models of systemic lupus erythematosus.

5. Origins of the concept of collagen-vascular diseases.

6. ARA Kunkel memorial lecture. Murine lupus. A model for human autoimmunity.

Review 7. Autoantibodies to nuclear antigens (ANA): their immunobiology and medicine.

8. Immunogenetics of juvenile chronic arthritis.

9. Association of antibody to histone complex H2A-H2B with symptomatic procainamide-induced lupus.

10. Molecular mimicry. Yeast histone H3-induced experimental autoimmune uveitis.

Review 1. Antiphospholipid antibodies in paediatrics.