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Literature DB >> 24061386

Single-base DNA discrimination via transverse ionic transport.

Abstract

We suggest the discrimination of single DNA bases via transverse ionic transport, namely by detecting the ionic current that flows in a channel while a single-stranded DNA is driven through an intersecting nanochannel. Our all-atom molecular dynamics simulations indeed show that the ionic currents of the four bases are statistically distinct, thus offering another possible approach to sequencing DNA.

Entities: Chemical

Mesh：

Substances：
DNA, Single-Stranded
Ions

Year: 2013 PMID： 24061386 PMCID： PMC4516905 DOI： 10.1088/0957-4484/24/41/415101

Source DB: PubMed Journal: Nanotechnology ISSN： 0957-4484 Impact factor: 3.874

20 in total

1. DNA translocation through graphene nanopores.

Authors: Christopher A Merchant; Ken Healy; Meni Wanunu; Vishva Ray; Neil Peterman; John Bartel; Michael D Fischbein; Kimberly Venta; Zhengtang Luo; A T Charlie Johnson; Marija Drndić
Journal: Nano Lett Date: 2010-08-11 Impact factor: 11.189

2. DNA translocation through graphene nanopores.

Authors: Grégory F Schneider; Stefan W Kowalczyk; Victor E Calado; Grégory Pandraud; Henny W Zandbergen; Lieven M K Vandersypen; Cees Dekker
Journal: Nano Lett Date: 2010-08-11 Impact factor: 11.189

3. Deciphering ionic current signatures of DNA transport through a nanopore.

Authors: Aleksei Aksimentiev
Journal: Nanoscale Date: 2010-02-02 Impact factor: 7.790

4. Electronic signature of DNA nucleotides via transverse transport.

Authors: Michael Zwolak; Massimiliano Di Ventra
Journal: Nano Lett Date: 2005-03 Impact factor: 11.189

5. Scalable molecular dynamics with NAMD.

Authors: James C Phillips; Rosemary Braun; Wei Wang; James Gumbart; Emad Tajkhorshid; Elizabeth Villa; Christophe Chipot; Robert D Skeel; Laxmikant Kalé; Klaus Schulten
Journal: J Comput Chem Date: 2005-12 Impact factor: 3.376

Review 6. Nanopore analytics: sensing of single molecules.

Authors: Stefan Howorka; Zuzanna Siwy
Journal: Chem Soc Rev Date: 2009-06-15 Impact factor: 54.564

7. Nanogap detector inside nanofluidic channel for fast real-time label-free DNA analysis.

Authors: Xiaogan Liang; Stephen Y Chou
Journal: Nano Lett Date: 2008-04-17 Impact factor: 11.189

8. Effect of noise on DNA sequencing via transverse electronic transport.

Authors: Matt Krems; Michael Zwolak; Yuriy V Pershin; Massimiliano Di Ventra
Journal: Biophys J Date: 2009-10-07 Impact factor: 4.033

9. Electronic signatures of all four DNA nucleosides in a tunneling gap.

Authors: Shuai Chang; Shuo Huang; Jin He; Feng Liang; Peiming Zhang; Shengqing Li; Xiang Chen; Otto Sankey; Stuart Lindsay
Journal: Nano Lett Date: 2010-03-10 Impact factor: 11.189

Review 10. The potential and challenges of nanopore sequencing.

Authors: Daniel Branton; David W Deamer; Andre Marziali; Hagan Bayley; Steven A Benner; Thomas Butler; Massimiliano Di Ventra; Slaven Garaj; Andrew Hibbs; Xiaohua Huang; Stevan B Jovanovich; Predrag S Krstic; Stuart Lindsay; Xinsheng Sean Ling; Carlos H Mastrangelo; Amit Meller; John S Oliver; Yuriy V Pershin; J Michael Ramsey; Robert Riehn; Gautam V Soni; Vincent Tabard-Cossa; Meni Wanunu; Matthew Wiggin; Jeffery A Schloss
Journal: Nat Biotechnol Date: 2008-10 Impact factor: 54.908

4 in total