Literature DB >> 24060852

Regioselective Heck reaction of aliphatic olefins and aryl halides.

Liena Qin1, Hajime Hirao, Jianrong Steve Zhou.   

Abstract

A regioselective Heck reaction of aliphatic olefins and aryl bromides is realized at internal carbons of olefins. Methanol solvent promoted halide ionization from neutral arylpalladium halide complexes via hydrogen bonding, so as to create cationic aryl-Pd species for regioselective olefin insertion.

Entities:  

Year:  2013        PMID： 24060852     DOI： 10.1039/c3cc45911j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  Nickel Catalysis: Synergy between Method Development and Total Synthesis.

Authors:  Eric A Standley; Sarah Z Tasker; Kim L Jensen; Timothy F Jamison
Journal:  Acc Chem Res       Date:  2015-04-23       Impact factor: 22.384

2.  Regioselective aerobic oxidative Heck reactions with electronically unbiased alkenes: efficient access to α-alkyl vinylarenes.

Authors:  Changwu Zheng; Shannon S Stahl
Journal:  Chem Commun (Camb)       Date:  2015-08-18       Impact factor: 6.222

3.  Iridium-Catalyzed α-Selective Arylation of Styrenes by Dual C-H Functionalization.

Authors:  Phillippa Cooper; Giacomo E M Crisenza; Lyman J Feron; John F Bower
Journal:  Angew Chem Int Ed Engl       Date:  2018-09-26       Impact factor: 15.336

4.  Bromide-assisted chemoselective Heck reaction of 3-bromoindazoles under high-speed ball-milling conditions: synthesis of axitinib.

Authors:  Jingbo Yu; Zikun Hong; Xinjie Yang; Yu Jiang; Zhijiang Jiang; Weike Su
Journal:  Beilstein J Org Chem       Date:  2018-04-06       Impact factor: 2.883
  4 in total

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