PURPOSE: To compare percutaneous needle fasciotomy (PNF) with collagenase injection in the treatment of Dupuytren contracture. METHODS: A retrospective review was performed for patients with Dupuytren disease treated with PNF or collagenase. Range of motion, patient satisfaction, and complications were recorded. RESULTS: There were 29 patients in the collagenase group with mean baseline contractures of 40° for 22 affected metacarpophalangeal joints and 50° for 12 affected proximal interphalangeal joints. The PNF group was composed of 30 patients with mean baseline contractures of 37° for 32 affected metacarpophalangeal joints and 41° for 18 affected proximal interphalangeal joints. All patients were observed for a minimum of 3 months. Clinical success (reduction of contracture within 0° to 5° of normal) was accomplished in 35 of 50 joints (67%) in the PNF group and in 19 of 34 joints (56%) in the collagenase group. Patient satisfaction was similar between groups. Only minor complications were observed, including skin tears, ecchymosis, edema, pruritus, and lymphadenopathy. CONCLUSIONS: In the short term, both PNF and collagenase have similar clinical outcomes and patient satisfaction. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic III.
PURPOSE: To compare percutaneous needle fasciotomy (PNF) with collagenase injection in the treatment of Dupuytren contracture. METHODS: A retrospective review was performed for patients with Dupuytren disease treated with PNF or collagenase. Range of motion, patient satisfaction, and complications were recorded. RESULTS: There were 29 patients in the collagenase group with mean baseline contractures of 40° for 22 affected metacarpophalangeal joints and 50° for 12 affected proximal interphalangeal joints. The PNF group was composed of 30 patients with mean baseline contractures of 37° for 32 affected metacarpophalangeal joints and 41° for 18 affected proximal interphalangeal joints. All patients were observed for a minimum of 3 months. Clinical success (reduction of contracture within 0° to 5° of normal) was accomplished in 35 of 50 joints (67%) in the PNF group and in 19 of 34 joints (56%) in the collagenase group. Patient satisfaction was similar between groups. Only minor complications were observed, including skin tears, ecchymosis, edema, pruritus, and lymphadenopathy. CONCLUSIONS: In the short term, both PNF and collagenase have similar clinical outcomes and patient satisfaction. TYPE OF STUDY/LEVEL OF EVIDENCE: Therapeutic III.
Authors: Takashi Hirase; Rishi Suresh; Michael O Cotton; Alex Han; Matthew B Burn; Joshua D Harris; Shari R Liberman Journal: J Hand Microsurg Date: 2020-12-31
Authors: Mikko P Räisänen; Teemu Karjalainen; Harry Göransson; Aleksi Reito; Hannu Kautiainen; Antti Malmivaara; Olli V Leppänen Journal: BMJ Open Date: 2018-03-28 Impact factor: 2.692
Authors: Jeremy N Rodrigues; Giles W Becker; Cathy Ball; Weiya Zhang; Henk Giele; Jonathan Hobby; Anna L Pratt; Tim Davis Journal: Cochrane Database Syst Rev Date: 2015-12-09