Literature DB >> 24057542

Epidural metastasis in chemoresistant Wilms' tumor with perilobar nephroblastomatosis.

H Kurosawa1, H Kurumada, E Haga, K Sugita, M Eguchi, T Furukawa, Y Kurosu, T Fujiwara, J Hata.   

Abstract

An 8-year-old boy with vertebral and epidural metastases was diagnosed with Wilms' tumor associated with perilobar nephroblastomatosis (NB) based on histologic examination. During combined chemotherapy with vincristine, actinomycin D, doxorubicin, and cyclophosphamide (NWTS-3 J protocol), a rapid increase in tumor size was observed. The treatment was replaced with etoposide and carboplatin (JET regimen). A transient response was sustained for 5 months during this chemotherapy. However, regrowth of the tumor was observed and the patient died 11 months after the initial chemotherapy.

Entities:  

Year:  2013        PMID： 24057542     DOI： 10.1007/BF00183751

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN： 0179-0358            Impact factor:   1.827


  17 in total

1.  Nodular renal blastema. Definition and possible significance.

Authors:  K E Bove; H Koffler; A J McAdams
Journal:  Cancer       Date:  1969-08       Impact factor: 6.860

2.  Etoposide and carboplatin: a highly effective combination in relapsed or refractory Wilms' tumor--a phase II study by the French Society of Pediatric Oncology.

Authors:  F Pein; M F Tournade; J M Zucker; M Brunat-Mentigny; A Deville; P Boutard; F Dusol; J C Gentet; E Legall; F Mechinaud
Journal:  J Clin Oncol       Date:  1994-05       Impact factor: 44.544

3.  Solitary spinal metastasis from Wilms' tumor.

Authors:  T E Sumner; J E Crowe; M D Parker; J P White
Journal:  Pediatr Radiol       Date:  1980-04

4.  Recurrence of Wilms tumor after apparent cure.

Authors:  T H Kim; G S Zaatari; E S Baum; N Jaffe; B Cushing; R L Chard; G T Zwiren; J B Beckwith
Journal:  J Pediatr       Date:  1985-07       Impact factor: 4.406

5.  High-dose carboplatin in combination with etoposide (JET regimen) for childhood brain tumors.

Authors:  M A Castello; A Clerico; G Deb; C Dominici; P Fidani; A Donfrancesco
Journal:  Am J Pediatr Hematol Oncol       Date:  1990

Review 6.  Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms' tumor.

Authors:  J B Beckwith; N B Kiviat; J F Bonadio
Journal:  Pediatr Pathol       Date:  1990

7.  Treatment of Wilms' tumor. Results of the Third National Wilms' Tumor Study.

Authors:  G J D'Angio; N Breslow; J B Beckwith; A Evans; H Baum; A deLorimier; D Fernbach; E Hrabovsky; B Jones; P Kelalis
Journal:  Cancer       Date:  1989-07-15       Impact factor: 6.860

8.  Etoposide in relapsed or refractory Wilms' tumor: a phase II study by the French Society of Pediatric Oncology and the United Kingdom Children's Cancer Study Group.

Authors:  F Pein; R Pinkerton; M F Tournade; M Brunat-Mentigny; G Levitt; G Margueritte; H Rubie; D Sommelet; A Thyss; J M Zücker
Journal:  J Clin Oncol       Date:  1993-08       Impact factor: 44.544

9.  Spinal cord compression in widely metastatic Wilms' tumor. Paraplegia in two children with anaplastic Wilms' tumor.

Authors:  D H Ebb; H Kerasidis; G Vezina; R J Packer; S Carabell; P Ivy
Journal:  Cancer       Date:  1992-06-01       Impact factor: 6.860

10.  Epidural metastasis by Wilms' tumor.

Authors:  C T Bever; M R Koenigsberger; J L Antunes; J A Wolff
Journal:  Am J Dis Child       Date:  1981-07
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