Literature DB >> 24057144

Barriers to accessing biologic treatment for rheumatoid arthritis in Greece: the unseen impact of the fiscal crisis--the Health Outcomes Patient Environment (HOPE) study.

Kyriakos Souliotis1, Manto Papageorgiou, Anastasia Politi, Dimitrios Ioakeimidis, Prodromos Sidiropoulos.   

Abstract

The latest regulatory change in the distribution system of biologic disease-modifying, antirheumatic drugs limited their sale only through the designated pharmacies of the National Organization for Healthcare Services Provision (EOPYY) or the National Health System (NHS) hospitals, adding to the complexity of access to effective treatment for rheumatoid arthritis (RA) in Greece. The aim of this paper was to assess the barriers to access RA treatment, by recording patients', rheumatologists' and EOPYY pharmacists' experiences. One twenty-three patients, 12 rheumatologists and 27 pharmacists from Athens and other urban areas in Greece participated in the study. Three types of standardized questionnaires were used to elicit information from each group of respondents using the method of personal interview for patients and the method of postal survey for doctors and pharmacists. During the last year, 26% of patients encountered problems in accessing their rheumatologist and 49% of patients experienced difficulties in accessing their medication. Ninety-two percent of rheumatologists and 96% of pharmacists confirmed that patients experience difficulties in accessing RA medication. The most commonly reported reasons for reduced access to medical treatment were travel difficulties and long distance from doctor's clinic, as well as delays in booking an appointment. The most frequently reported barriers to access pharmaceutical treatment were difficulties in the prescription process, distance from EOPYY pharmacies and medicine shortages in NHS hospitals. The study showed that RA patients are facing increased barriers to access timely and effective treatment. Redesign of the current system of distribution ensuring the operation of additional points of sale is deemed necessary.

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Year:  2013        PMID: 24057144     DOI: 10.1007/s00296-013-2866-1

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN: 0172-8172            Impact factor:   2.631


  21 in total

1.  Early versus delayed treatment in patients with recent-onset rheumatoid arthritis: comparison of two cohorts who received different treatment strategies.

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Journal:  Am J Med       Date:  2001-10-15       Impact factor: 4.965

2.  Do rheumatoid arthritis patients have equal access to treatment with new medicines?: tumour necrosis factor-alpha inhibitors use in four European countries.

Authors:  Joëlle M Hoebert; Aukje K Mantel-Teeuwisse; Liset van Dijk; Johannes W J Bijlsma; Hubert G M Leufkens
Journal:  Health Policy       Date:  2011-11-12       Impact factor: 2.980

3.  American College of Rheumatology 2008 recommendations for the use of nonbiologic and biologic disease-modifying antirheumatic drugs in rheumatoid arthritis.

Authors:  Kenneth G Saag; Gim Gee Teng; Nivedita M Patkar; Jeremy Anuntiyo; Catherine Finney; Jeffrey R Curtis; Harold E Paulus; Amy Mudano; Maria Pisu; Mary Elkins-Melton; Ryan Outman; Jeroan J Allison; Maria Suarez Almazor; S Louis Bridges; W Winn Chatham; Marc Hochberg; Catherine MacLean; Ted Mikuls; Larry W Moreland; James O'Dell; Anthony M Turkiewicz; Daniel E Furst
Journal:  Arthritis Rheum       Date:  2008-06-15

Review 4.  The costs of rheumatoid arthritis: an international long-term view.

Authors:  K M Pugner; D I Scott; J W Holmes; K Hieke
Journal:  Semin Arthritis Rheum       Date:  2000-04       Impact factor: 5.532

5.  Access to healthcare services among persons with osteoarthritis and rheumatoid arthritis.

Authors:  Kristofer J Hagglund; Mary J Clark; Shelley A Hilton; James E Hewett
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Review 6.  Review of eight pharmacoeconomic studies of the value of biologic DMARDs (adalimumab, etanercept, and infliximab) in the management of rheumatoid arthritis.

Authors:  Quan V Doan; Chiun-Fang Chiou; Robert W Dubois
Journal:  J Manag Care Pharm       Date:  2006-09

7.  Early referral, diagnosis, and treatment of rheumatoid arthritis: evidence for changing medical practice.

Authors:  S Irvine; R Munro; D Porter
Journal:  Ann Rheum Dis       Date:  1999-08       Impact factor: 19.103

8.  Optimal care for rheumatoid arthritis: a focus group study.

Authors:  Sasha Bernatsky; Debbie Feldman; Mirella De Civita; Jeannie Haggerty; Pierre Tousignant; Jean Legaré; Michel Zummer; Tim Meagher; Christopher Mill; Mark Roper; Jennifer Lee
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9.  The relationship between disease activity and radiologic progression in patients with rheumatoid arthritis: a longitudinal analysis.

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Journal:  Arthritis Rheum       Date:  2004-07

Review 10.  EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs.

Authors:  Josef S Smolen; Robert Landewé; Ferdinand C Breedveld; Maxime Dougados; Paul Emery; Cecile Gaujoux-Viala; Simone Gorter; Rachel Knevel; Jackie Nam; Monika Schoels; Daniel Aletaha; Maya Buch; Laure Gossec; Tom Huizinga; Johannes W J W Bijlsma; Gerd Burmester; Bernard Combe; Maurizio Cutolo; Cem Gabay; Juan Gomez-Reino; Marios Kouloumas; Tore K Kvien; Emilio Martin-Mola; Iain McInnes; Karel Pavelka; Piet van Riel; Marieke Scholte; David L Scott; Tuulikki Sokka; Guido Valesini; Ronald van Vollenhoven; Kevin L Winthrop; John Wong; Angela Zink; Désirée van der Heijde
Journal:  Ann Rheum Dis       Date:  2010-05-05       Impact factor: 19.103

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  18 in total

1.  Access to Care for Multiple Sclerosis in Times of Economic Crisis in Greece--the HOPE II Study.

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Journal:  Int J Health Policy Manag       Date:  2015-09-27

2.  Enduring financial crisis in Greece: prevalence and correlates of major depression and suicidality.

Authors:  Marina Economou; Elias Angelopoulos; Lily Evangelia Peppou; Kyriakos Souliotis; Chara Tzavara; Konstantinos Kontoangelos; Michael Madianos; Costas Stefanis
Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2016-05-13       Impact factor: 4.328

3.  Economic Distress in Families with a Member Suffering from Severe Mental Illness: Illness Burden or Financial Crisis? Evidence from Greece.

Authors:  Alexandra Palli; Lily Evangelia Peppou; Marina Economou; Konstantinos Kontoangelos; Kyriakos Souliotis; Antonia Paschali
Journal:  Community Ment Health J       Date:  2020-07-07

4.  Protective effect of taraxasterol against rheumatoid arthritis by the modulation of inflammatory responses in mice.

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5.  Economic evaluation of anti-TNF agents for patients with rheumatoid arthritis in Greece.

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Review 6.  Access to an optimal treatment. Current situation.

Authors:  Manuel F Ugarte-Gil; Adriana M R Silvestre; Bernardo A Pons-Estel
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7.  Access to treatment for Hepatitis C among injection drug users: results from the cross-sectional HOPE IV study.

Authors:  Kyriakos Souliotis; Eirini Agapidaki; Manto Papageorgiou; Niki Voudouri; Xenophon Contiades
Journal:  Int J Equity Health       Date:  2017-06-14

8.  Accessibility to biologics and its impact on disease activity and quality of life in patients with rheumatoid arthritis in Kuwait.

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Journal:  Clin Rheumatol       Date:  2020-10-12       Impact factor: 2.980

Review 9.  Drug Shortage: Causes, Impact, and Mitigation Strategies.

Authors:  Sundus Shukar; Fatima Zahoor; Khezar Hayat; Amna Saeed; Ali Hassan Gillani; Sumaira Omer; Shuchen Hu; Zaheer-Ud-Din Babar; Yu Fang; Caijun Yang
Journal:  Front Pharmacol       Date:  2021-07-09       Impact factor: 5.810

10.  Estimating the Fiscal Effects of Public Pharmaceutical Expenditure Reduction in Greece.

Authors:  Kyriakos Souliotis; Manto Papageorgiou; Anastasia Politi; Nikolaos Frangos; Yiannis Tountas
Journal:  Front Public Health       Date:  2015-08-31
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