Madeleine Grigg-Damberger1, Frank Ralls. 1. aDepartment of Neurology, University of New Mexico School of Medicine bPediatric Sleep Medicine Services, University Hospital Sleep Disorders Center cClinical Neurodiagnostic Laboratory, University of New Mexico Medical Center dDepartment of Internal Medicine eAdult Sleep Medicine Services fProgram in Sleep Medicine, University of New Mexico Hospital Sleep Disorders Center, Albuquerque, New Mexico, USA.
Abstract
PURPOSE OF REVIEW: This review describes recent research in pediatric behavioral insomnias in neurodevelopmental disorders and their treatment. RECENT FINDINGS: Insomnia in children with autism spectrum disorder (ASD) and other neurodevelopmental disorders (NDDs) is typically complex, chronic, and difficult to adequately control. Abnormalities in genetic and/or epigenetic regulation of sleep/wakefulness and its timing predispose patients with NDD to insomnia, although poor sleep hygiene, maladaptive associations, and limit-setting are likely to contribute. Parents are agents for change in problematic sleep behaviors in patients with NDD. We review the benefits of behavioral therapies and melatonin to treat sleep problems in children with NDD. Problematic sleep is so prevalent in some neurodevelopmental syndromes (Rett, Angelman, Williams, and Smith-Magenis) that it is part of their diagnostic criteria. SUMMARY: Children and adolescents with neurological disorders frequently have complex sleep disorders that require treatment. Understanding the basic pathology and treatment strategies provides an opportunity to improve well being and quality of life in those affected by NDD and their families.
PURPOSE OF REVIEW: This review describes recent research in pediatric behavioral insomnias in neurodevelopmental disorders and their treatment. RECENT FINDINGS:Insomnia in children with autism spectrum disorder (ASD) and other neurodevelopmental disorders (NDDs) is typically complex, chronic, and difficult to adequately control. Abnormalities in genetic and/or epigenetic regulation of sleep/wakefulness and its timing predispose patients with NDD to insomnia, although poor sleep hygiene, maladaptive associations, and limit-setting are likely to contribute. Parents are agents for change in problematic sleep behaviors in patients with NDD. We review the benefits of behavioral therapies and melatonin to treat sleep problems in children with NDD. Problematic sleep is so prevalent in some neurodevelopmental syndromes (Rett, Angelman, Williams, and Smith-Magenis) that it is part of their diagnostic criteria. SUMMARY:Children and adolescents with neurological disorders frequently have complex sleep disorders that require treatment. Understanding the basic pathology and treatment strategies provides an opportunity to improve well being and quality of life in those affected by NDD and their families.
Authors: Simonne Cohen; Russell Conduit; Steven W Lockley; Shantha Mw Rajaratnam; Kim M Cornish Journal: J Neurodev Disord Date: 2014-12-11 Impact factor: 4.025
Authors: Stephanie R Keller; Eric J Mallack; Jennifer P Rubin; Jennifer A Accardo; Jennifer A Brault; Camille S Corre; Camila Elizondo; Jennifer Garafola; April C Jackson-Garcia; Jullie Rhee; Elisa Seeger; Kaprice C Shullanberger; Amanda Tourjee; Melissa K Trovato; Amy T Waldman; Jenna L Wallace; Michael R Wallace; Klaus Werner; Angela White; Kevin C Ess; Catherine Becker; Florian S Eichler Journal: J Child Neurol Date: 2020-09-02 Impact factor: 1.987