| Literature DB >> 24054327 |
Haitao Wen1, Edward A Miao, Jenny P-Y Ting.
Abstract
A major function of a subfamily of NLR (nucleotide-binding domain, leucine-rich repeat containing, or NOD-like receptor) proteins is in inflammasome activation, which has been implicated in a multitude of disease models and human diseases. This work will highlight key progress in understanding the mechanisms that activate the best-studied NLRs (NLRP3, NLRC4, NAIP, and NLRP1) and in uncovering inflammasome NLRs.Entities:
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Year: 2013 PMID: 24054327 PMCID: PMC3835203 DOI: 10.1016/j.immuni.2013.08.037
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745