| Literature DB >> 24050232 |
Abstract
Thyroid neoplasias represent among the fastest growing cancers. While surgery has become the treatment of choice for most thyroid tumors, many require chemotherapy. In this review, we examine the contributions of work in the fruit fly Drosophila toward multiple endocrine neoplasia type 2 (MEN2), a Ret-based disease to which recent Drosophila models have proven useful both for understanding disease mechanism as well as helping identify new generation therapeutics.Entities:
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Year: 2013 PMID： 24050232 PMCID： PMC3779345 DOI： 10.1016/j.ddtec.2012.09.004
Source DB: PubMed Journal: Drug Discov Today Technol ISSN： 1740-6749