Literature DB >> 24049274

Successful treatment of verruca vulgaris with Thuja occidentalis in a renal allograft recipient.

R Joseph1, S A Pulimood, P Abraham, G T John.   

Abstract

Human papillomavirus-driven verruca vulgaris infection is common in solid organ transplant recipients and increases the risk for squamous cell carcinoma. The available treatment modalities have limited response. We report a renal allograft recipient who presented with multiple warts not responding to cryotherapy and radiosurgery with one turning malignant, needing amputation of the finger. An extract from Thuja occidentalis (White cedar tree) cured the resistant warts on the other fingers, leaving only superficial scars and without affecting allograft function. We have reviewed the pharmacological and clinical properties of T. occidentalis.

Entities:  

Keywords:  Renal transplantation; Thuja occidentalis; squamous cell carcinoma; verruca vulgaris

Year:  2013        PMID: 24049274      PMCID: PMC3764712          DOI: 10.4103/0971-4065.116316

Source DB:  PubMed          Journal:  Indian J Nephrol        ISSN: 0971-4065


  6 in total

1.  Effects of an orally applied aqueous-ethanolic extract of a mixture of Thujae occidentalis herba, Baptisiae tinctoriae radix, Echinaceae purpureae radix and Echinaceae pallidae radix on antibody response against sheep red blood cells in mice.

Authors:  C Bodinet; J Freudenstein
Journal:  Planta Med       Date:  1999-12       Impact factor: 3.352

2.  Effect of an orally applied herbal immunomodulator on cytokine induction and antibody response in normal and immunosuppressed mice.

Authors:  C Bodinet; U Lindequist; E Teuscher; J Freudenstein
Journal:  Phytomedicine       Date:  2002-10       Impact factor: 5.340

3.  Histopathology of skin lesions with warty appearance in renal allograft recipients.

Authors:  Fariba Iraji; Asadollah Kiani; Shahrzad Shahidi; Ramesh Vahabi
Journal:  Am J Dermatopathol       Date:  2002-08       Impact factor: 1.533

4.  Activation of CD4-positive T cells by polysaccharide fractions isolated from the Cupressaceae Thuja occidentalis L. (Arborvitae).

Authors:  S H Gohla; H D Haubeck; S Schrum; H Soltau; R D Neth
Journal:  Haematol Blood Transfus       Date:  1989

Review 5.  Topical treatments for cutaneous warts.

Authors:  S Gibbs; I Harvey
Journal:  Cochrane Database Syst Rev       Date:  2006-07-19

Review 6.  Use of proliferation signal inhibitors in non-melanoma skin cancer following renal transplantation.

Authors:  J W de Fijter
Journal:  Nephrol Dial Transplant       Date:  2007-05       Impact factor: 5.992

  6 in total

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