Literature DB >> 24047821

Operative and nonoperative treatment approaches for lumbar degenerative disc disease have similar long-term clinical outcomes among patients with positive discography.

Justin S Smith1, Gursukhman Sidhu2, Ken Bode2, David Gendelberg3, Mitchell Maltenfort2, David Ibrahimi4, Christopher I Shaffrey4, Alexander R Vaccaro2.   

Abstract

OBJECTIVE: It remains unclear whether fusion for lumbar degenerative disc disease with positive discography produces better outcomes compared with nonoperative treatment. The aim of this study was to compare outcomes of patients with discography-concordant lumbar degenerative disc disease electing for fusion versus nonoperative treatment.
METHODS: We retrospectively reviewed consecutive patients with back pain and concordant lumbar discogram who were offered fusion. Follow-up questionnaires included pain score, Oswestry disability index, short form-12, and satisfaction scale. Patients were stratified based on whether they elected for fusion or nonoperative treatment.
RESULTS: Overall follow-up was 48% (96/200). Patients lacking follow-up were slightly older (P = 0.021) and less likely to be smokers (P = 0.013). Between patients with and without follow-up, there were no significant differences in pain score at initial visit, body mass index, or gender (P ≥ 0.40). The 96 patients for whom follow-up was obtained included 53 in the operative and 43 in the nonoperative groups. At baseline, there were no significant differences between these groups based on age, pain score, body mass index, smoking, or gender (P ≥ 0.25). Mean follow-up was 63 months for operative and 58 months for nonoperative patients (P = 0.20). The mean pain score at last follow-up improved significantly for operative and nonoperative patients (P < 0.001). At follow-up, operative and nonoperative groups did not differ significantly with regard to pain scores, Oswestry disability index, short form-12, or satisfaction scale.
CONCLUSIONS: Comparison of long-term outcomes for patients with back pain and concordant discography did not demonstrate a significant difference in outcome measures of pain, health status, satisfaction, or disability based on whether the patient elected for fusion or nonoperative treatment.
Copyright © 2014 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Degenerative disc disease; Discogram; Discography; Fusion; Lumbar; Outcomes; Spine; Surgery

Mesh:

Year:  2013        PMID: 24047821     DOI: 10.1016/j.wneu.2013.09.013

Source DB:  PubMed          Journal:  World Neurosurg        ISSN: 1878-8750            Impact factor:   2.104


  3 in total

1.  Magnetic resonance spectroscopy (MRS) can identify painful lumbar discs and may facilitate improved clinical outcomes of lumbar surgeries for discogenic pain.

Authors:  Matthew G Gornet; James Peacock; John Claude; Francine W Schranck; Anne G Copay; Robert K Eastlack; Ryan Benz; Adam Olshen; Jeffrey C Lotz
Journal:  Eur Spine J       Date:  2019-01-04       Impact factor: 3.134

2.  Primary pain generator identification by CT-SPECT in a patient with low back pain: a case report.

Authors:  Gabriel Tender; Adriana Constantinescu; Andrew Conger; Anthony DiGiorgio
Journal:  BMC Res Notes       Date:  2017-03-21

Review 3.  Smoking and degenerative spinal disease: A systematic review.

Authors:  Niharika Rajesh; Jigishaa Moudgil-Joshi; Chandrasekaran Kaliaperumal
Journal:  Brain Spine       Date:  2022-08-07
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.