Literature DB >> 24046191

Evidence for the involvement of epigenetics in the progression of renal fibrogenesis.

Björn Tampe1, Michael Zeisberg.   

Abstract

Epigenetics are omnipresent in eukaryotic cells and influence cell differentiation and maintenance of cell metabolism in health and disease. Here, we discuss how the 'second genetic code' impacts the fate of the injured kidney. We provide a glimpse of how recent insights into epigenetic mechanisms of chronic kidney disease might lead to novel diagnostic and therapeutic tools.

Entities:  

Keywords:  epigenetic; histone modification; hydroxymethylation; kidney fibrosis; methylation

Mesh：

Year:  2013        PMID： 24046191     DOI： 10.1093/ndt/gft361

Source DB:  PubMed          Journal:  Nephrol Dial Transplant        ISSN： 0931-0509            Impact factor:   5.992


  13 in total

Review 1.  TGF-β: the master regulator of fibrosis.

Authors:  Xiao-Ming Meng; David J Nikolic-Paterson; Hui Yao Lan
Journal:  Nat Rev Nephrol       Date:  2016-04-25       Impact factor: 28.314

Review 2.  A perspective on chronic kidney disease progression.

Authors:  Jianyong Zhong; Hai-Chun Yang; Agnes B Fogo
Journal:  Am J Physiol Renal Physiol       Date:  2016-12-14

3.  Targeting histone methyltransferase enhancer of zeste homolog-2 inhibits renal epithelial-mesenchymal transition and attenuates renal fibrosis.

Authors:  Xiaoxu Zhou; Chongxiang Xiong; Evelyn Tolbert; Ting C Zhao; George Bayliss; Shougang Zhuang
Journal:  FASEB J       Date:  2018-05-18       Impact factor: 5.191

4.  Enhancer of Zeste Homolog 2 Inhibition Attenuates Renal Fibrosis by Maintaining Smad7 and Phosphatase and Tensin Homolog Expression.

Authors:  Xiaoxu Zhou; Xiujuan Zang; Murugavel Ponnusamy; Monica V Masucci; Evelyn Tolbert; Rujun Gong; Ting C Zhao; Na Liu; George Bayliss; Lance D Dworkin; Shougang Zhuang
Journal:  J Am Soc Nephrol       Date:  2015-12-23       Impact factor: 10.121

5.  Targeting lysine-specific demethylase 1A inhibits renal epithelial-mesenchymal transition and attenuates renal fibrosis.

Authors:  Xiaoqin Zhang; Linda Xiaoyan Li; Chen Yu; Karl A Nath; Shougang Zhuang; Xiaogang Li
Journal:  FASEB J       Date:  2022-01       Impact factor: 5.834

6.  Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease.

Authors:  Björn Tampe; Desiree Tampe; Elisabeth M Zeisberg; Gerhard A Müller; Wibke Bechtel-Walz; Michael Koziolek; Raghu Kalluri; Michael Zeisberg
Journal:  EBioMedicine       Date:  2015-01       Impact factor: 8.143

7.  Immunotherapy With Human Gamma Delta T Cells-Synergistic Potential of Epigenetic Drugs?

Authors:  Jaydeep Bhat; Léonce Kouakanou; Christian Peters; Zhinan Yin; Dieter Kabelitz
Journal:  Front Immunol       Date:  2018-03-13       Impact factor: 7.561

8.  Histone Deacetylase 11 Contributes to Renal Fibrosis by Repressing KLF15 Transcription.

Authors:  Lei Mao; Li Liu; Tao Zhang; Hao Qin; Xiaoyan Wu; Yong Xu
Journal:  Front Cell Dev Biol       Date:  2020-04-17

9.  Trichostatin A Alleviates Renal Interstitial Fibrosis Through Modulation of the M2 Macrophage Subpopulation.

Authors:  Wei-Cheng Tseng; Ming-Tsun Tsai; Nien-Jung Chen; Der-Cherng Tarng
Journal:  Int J Mol Sci       Date:  2020-08-19       Impact factor: 5.923

10.  Precision renal medicine: a roadmap towards targeted kidney fibrosis therapies.

Authors:  Michael Zeisberg; Elisabeth M Zeisberg
Journal:  Fibrogenesis Tissue Repair       Date:  2015-09-01
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