| Literature DB >> 24045884 |
Jing Lu Liang1, Umair Javed, Seung Ho Lee, Jae Gyu Park, Yurngdong Jahng.
Abstract
A series of 6-deoxymollugins were prepared five steps from benzaldehyde and its derivatives via phenylboronic acid-catalyzed chromenylation as a key step. Their inhibitory activities against tyrosinase from mushroom were evaluated to show that the parent, methyl 2,2-dimethyl-2H-benzo[h]chromene-5-carboxylate (9a) showed best and promising inhibitory activity at IC50 = 18.3 μM.Entities:
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Year: 2013 PMID： 24045884 DOI： 10.1007/s12272-013-0240-1
Source DB: PubMed Journal: Arch Pharm Res ISSN： 0253-6269 Impact factor: 4.946