Literature DB >> 2404579

Radiolabeled antibodies: results and potential in cancer therapy.

S E Order1, A M Sleeper, G B Stillwagon, J L Klein, P K Leichner.   

Abstract

Radiolabeled antibodies are analyzed from the classical approach in radiation oncology being compared to geometric isotopic implants, external radiation, and tumor-dose response and energy of the isotope used for cytotoxicity. In addition, physiological factors that limit antibody uptake, varied routes of administration, toxicity of treatment, as well as present clinical progress are reviewed.

Entities:  

Mesh:

Substances:

Year:  1990        PMID: 2404579

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


  7 in total

1.  The scientific bases of cancer management: at the interface between fundamental research and clinical practice.

Authors:  M Tubiana
Journal:  J Cancer Res Clin Oncol       Date:  1991       Impact factor: 4.553

Review 2.  Activation of T lymphocytes for the adoptive immunotherapy of cancer.

Authors:  J J Sussman; S Shu; V K Sondak; A E Chang
Journal:  Ann Surg Oncol       Date:  1994-07       Impact factor: 5.344

3.  Modulation of drug-induced cytotoxicity by a bispecific monoclonal antibody that recognizes the epidermal growth factor receptor and doxorubicin.

Authors:  D Morelli; A Sardini; E Villa; M L Villa; S Ménard; M I Colnaghi; A Balsari
Journal:  Cancer Immunol Immunother       Date:  1994-03       Impact factor: 6.968

Review 4.  Monoclonal antibodies in imaging and therapy of colorectal cancer.

Authors:  M K Lange; E W Martin
Journal:  World J Surg       Date:  1991 Sep-Oct       Impact factor: 3.352

5.  Adriamycin(hydrazone)-antibody conjugates require internalization and intracellular acid hydrolysis for antitumor activity.

Authors:  G R Braslawsky; K Kadow; J Knipe; K McGoff; M Edson; T Kaneko; R S Greenfield
Journal:  Cancer Immunol Immunother       Date:  1991       Impact factor: 6.968

6.  Comparative biodistribution of indium- and yttrium-labeled B3 monoclonal antibody conjugated to either 2-(p-SCN-Bz)-6-methyl-DTPA (1B4M-DTPA) or 2-(p-SCN-Bz)-1,4,7,10-tetraazacyclododecane tetraacetic acid (2B-DOTA).

Authors:  L Camera; S Kinuya; K Garmestani; M W Brechbiel; C Wu; L H Pai; T J McMurry; O A Gansow; I Pastan; C H Paik
Journal:  Eur J Nucl Med       Date:  1994-07

7.  Therapy and imaging of pancreatic carcinoma xenografts with radioiodine-labeled chimeric monoclonal antibody A10 and its Fab fragment.

Authors:  T Kamigaki; M Yamamoto; H Ohyanagi; M Ohya; T Shimazoe; A Kono; W Ohtani; Y Narita; M Ohkubo; Y Saitoh
Journal:  Jpn J Cancer Res       Date:  1995-12
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.