Literature DB >> 24043241

Aerobic Fitness Is Disproportionately Low in Adult Burn Survivors Years After Injury.

Matthew S Ganio1, James Pearson, Zachary J Schlader, Robert Matthew Brothers, Rebekah A I Lucas, Eric Rivas, Karen J Kowalske, Craig G Crandall.   

Abstract

A maximal aerobic capacity below the 20th percentile is associated with an increased risk of all-cause mortality (Blair 1995). Adult Adult burn survivors have a lower aerobic capacity compared with nonburned adults when evaluated 38 ± 23 days postinjury (deLateur 2007). However, it is unknown whether burn survivors with well-healed skin grafts (ie, multiple years postinjury) also have low aerobic capacity. This project tested the hypothesis that aerobic fitness, as measured by maximal aerobic capacity (VO2max), is reduced in well-healed adult burn survivors when compared with normative values from nonburned individuals. Twenty-five burn survivors (36 ± 12 years old; 13 females) with well-healed split-thickness grafts (median, 16 years postinjury; range, 1-51 years) covering at least 17% of their BSA (mean, 40 ± 16%; range, 17-75%) performed a graded cycle ergometry exercise to test volitional fatigue. Expired gases and minute ventilation were measured via a metabolic cart for the determination of VO2max. Each subject's VO2max was compared with sex- and age-matched normative values from population data published by the American College of Sports Medicine, the American Heart Association, and recent epidemiological data (Aspenes 2011). Subjects had a VO2max of 29.4 ± 10.1 ml O2/kg body mass/min (median, 27.5; range, 15.9-53.3). The use of American College of Sports Medicine normative values showed that mean VO2max of the subjects was in the lower 24th percentile (median, 10th percentile). A total of 88% of the subjects had a VO2max below American Heart Association age-adjusted normative values. Similarly, 20 of the 25 subjects had a VO2max in the lower 25% percentile of recent epidemiological data. Relative to nongrafted subjects, 80 to 88% of the evaluated skin-graft subjects had a very low aerobic capacity. On the basis of these findings, adult burn survivors are disproportionally unfit relative to the general U.S. population, and this puts them at an increased risk of all-cause mortality (Blair 1995).

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Year:  2015        PMID: 24043241      PMCID: PMC3954961          DOI: 10.1097/BCR.0b013e3182a22915

Source DB:  PubMed          Journal:  J Burn Care Res        ISSN: 1559-047X            Impact factor:   1.845


  31 in total

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Authors:  G F Fletcher; G J Balady; E A Amsterdam; B Chaitman; R Eckel; J Fleg; V F Froelicher; A S Leon; I L Piña; R Rodney; D A Simons-Morton; M A Williams; T Bazzarre
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2.  Simplified chart for estimating burn areas.

Authors:  J A SAKSON
Journal:  Am J Surg       Date:  1959-11       Impact factor: 2.565

3.  Return to work and health-related quality of life after burn injury.

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Journal:  J Rehabil Med       Date:  2007-01       Impact factor: 2.912

Review 4.  Functional outcome after burns: a review.

Authors:  M E van Baar; M L Essink-Bot; I M M H Oen; J Dokter; H Boxma; E F van Beeck
Journal:  Burns       Date:  2005-12-22       Impact factor: 2.744

Review 5.  Restoration of function.

Authors:  Phala Helm; David N Herndon; Barbara Delateur
Journal:  J Burn Care Res       Date:  2007 Jul-Aug       Impact factor: 1.845

6.  Determinants of skeletal muscle catabolism after severe burn.

Authors:  D W Hart; S E Wolf; D L Chinkes; D C Gore; R P Mlcak; R B Beauford; M K Obeng; S Lal; W F Gold; R R Wolfe; D N Herndon
Journal:  Ann Surg       Date:  2000-10       Impact factor: 12.969

7.  Effects of a 12-wk resistance exercise program on skeletal muscle strength in children with burn injuries.

Authors:  O E Suman; R J Spies; M M Celis; R P Mlcak; D N Herndon
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8.  Effect of exercise training on pulmonary function in children with thermal injury.

Authors:  Oscar E Suman; Robert P Mlcak; David N Herndon
Journal:  J Burn Care Rehabil       Date:  2002 Jul-Aug

9.  Augmented exercise in the treatment of deconditioning from major burn injury.

Authors:  Barbara J de Lateur; Gina Magyar-Russell; Melissa G Bresnick; Faedra A Bernier; Michelle S Ober; Brian J Krabak; Linda Ware; Michael P Hayes; James A Fauerbach
Journal:  Arch Phys Med Rehabil       Date:  2007-12       Impact factor: 3.966

10.  Physical and psychologic rehabilitation outcomes for young adults burned as children.

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Journal:  Arch Phys Med Rehabil       Date:  2007-12       Impact factor: 3.966

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  15 in total

1.  Heat acclimation improves heat exercise tolerance and heat dissipation in individuals with extensive skin grafts.

Authors:  Zachary J Schlader; Matthew S Ganio; James Pearson; Rebekah A I Lucas; Daniel Gagnon; Eric Rivas; Karen J Kowalske; Craig G Crandall
Journal:  J Appl Physiol (1985)       Date:  2015-04-30

2.  Progressive exercise training improves maximal aerobic capacity in individuals with well-healed burn injuries.

Authors:  Steven A Romero; Gilbert Moralez; Manall F Jaffery; Mu Huang; Matthew N Cramer; Nadine Romain; Ken Kouda; Ronald G Haller; Craig G Crandall
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2019-08-21       Impact factor: 3.619

3.  Resting β-Adrenergic Blockade Does Not Alter Exercise Thermoregulation in Children With Burn Injury: A Randomized Control Trial.

Authors:  Eric Rivas; Serina J McEntire; David N Herndon; Oscar E Suman
Journal:  J Burn Care Res       Date:  2018-04-20       Impact factor: 1.845

4.  Children with Burn Injury Have Impaired Cardiac Output during Submaximal Exercise.

Authors:  Eric Rivas; David N Herndon; Kenneth C Beck; Oscar E Suman
Journal:  Med Sci Sports Exerc       Date:  2017-10       Impact factor: 5.411

5.  Nongrafted Skin Area Best Predicts Exercise Core Temperature Responses in Burned Humans.

Authors:  Matthew S Ganio; Zachary J Schlader; James Pearson; Rebekah A I Lucas; Daniel Gagnon; Eric Rivas; Karen J Kowalske; Craig G Crandall
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6.  Edward F. Adolph Distinguished Lecture. It's more than skin deep: thermoregulatory and cardiovascular consequences of severe burn injuries in humans.

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Journal:  J Appl Physiol (1985)       Date:  2021-11-04

7.  Cardiac Structure and Function in Well-Healed Burn Survivors.

Authors:  T Jake Samuel; Michael D Nelson; Aida Nasirian; Manall Jaffery; Gilbert Moralez; Steven A Romero; Matthew N Cramer; Mu Huang; Ken Kouda; Michinari Hieda; Satyam Sarma; Craig G Crandall
Journal:  J Burn Care Res       Date:  2019-02-20       Impact factor: 1.845

8.  The Effect of Passive Heat Stress and Exercise-Induced Dehydration on the Compensatory Reserve During Simulated Hemorrhage.

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Review 9.  Rehabilitative Exercise Training for Burn Injury.

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10.  Fluid restriction during exercise in the heat reduces tolerance to progressive central hypovolaemia.

Authors:  Zachary J Schlader; Daniel Gagnon; Eric Rivas; Victor A Convertino; Craig G Crandall
Journal:  Exp Physiol       Date:  2015-07-15       Impact factor: 2.969

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