Literature DB >> 24042270

Synthesis and antitumor activity of a series of osmium(VI) nitrido complexes bearing quinolinolato ligands.

Quan Tang1, Wen-Xiu Ni, Chi-Fai Leung, Wai-Lun Man, Kenneth King-Kwan Lau, Yimin Liang, Yun-Wah Lam, Wai-Yeung Wong, Shie-Ming Peng, Gui-Jian Liu, Tai-Chu Lau.   

Abstract

A series of osmium(VI) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that Os(VI)≡N is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs.

Entities:  

Mesh：

Substances：

Year:  2013        PMID： 24042270     DOI： 10.1039/c3cc42250j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  4 in total

1.  cis-Tetrachlorido-bis(indazole)osmium(iv) and its osmium(iii) analogues: paving the way towards the cis-isomer of the ruthenium anticancer drugs KP1019 and/or NKP1339.

Authors:  Gabriel E Büchel; Susanne Kossatz; Ahmad Sadique; Peter Rapta; Michal Zalibera; Lukas Bucinsky; Stanislav Komorovsky; Joshua Telser; Jörg Eppinger; Thomas Reiner; Vladimir B Arion
Journal:  Dalton Trans       Date:  2017-09-12       Impact factor: 4.390

2.  Synthesis and antitumor mechanism of a new iron(iii) complex with 5,7-dichloro-2-methyl-8-quinolinol as ligands.

Authors:  Bi-Qun Zou; Qi-Pin Qin; Yu-Xia Bai; Qian-Qian Cao; Ye Zhang; Yan-Cheng Liu; Zhen-Feng Chen; Hong Liang
Journal:  Medchemcomm       Date:  2017-02-01       Impact factor: 3.597

3.  Synthesis, crystal structure, cytotoxicity and action mechanism of a Rh(iii) complex with 8-hydroxy-2-methylquinoline as a ligand.

Authors:  Yun-Liang Zhang; Qi-Pin Qin; Qian-Qian Cao; Hong-Hua Han; Zhu-Ling Liu; Yan-Cheng Liu; Hong Liang; Zhen-Feng Chen
Journal:  Medchemcomm       Date:  2016-10-25       Impact factor: 3.597

4.  Eighteen 5,7-Dihalo-8-quinolinol and 2,2'-Bipyridine Co(II) Complexes as a New Class of Promising Anticancer Agents.

Authors:  Ting Meng; Qi-Pin Qin; Hua-Hong Zou; Kai Wang; Fu-Pei Liang
Journal:  ACS Med Chem Lett       Date:  2019-10-30       Impact factor: 4.345
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.