| Literature DB >> 24040651 |
Saad Makhseed1, Miloslav Machacek, Waleed Alfadly, Ahmad Tuhl, Mickey Vinodh, Tomas Simunek, Veronika Novakova, Pavel Kubat, Emil Rudolf, Petr Zimcik.
Abstract
Newly synthesized zinc phthalocyanine bearing sixteen quaternized imidazolyl moieties on the periphery displays high water-solubility, lack of aggregation and high singlet oxygen quantum yield in water (ΦΔ > 0.33). The in vitro tests indicated excellent anticancer photodynamic activity (EC50 = 36.7 nM) and low dark toxicity to non-cancerous cells (TC50 = 395 μM).Entities:
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Year: 2013 PMID： 24040651 DOI： 10.1039/c3cc44609c
Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222