Literature DB >> 24039022

A comparative CEST NMR study of slow conformational dynamics of small GTPases complexed with GTP and GTP analogues.

Dong Long1, Christopher B Marshall, Guillaume Bouvignies, Mohammad T Mazhab-Jafari, Matthew J Smith, Mitsuhiko Ikura, Lewis E Kay.   

Abstract

Entities:  

Keywords:  NMR spectroscopy; conformational dynamics; enzymes; protein dynamics; proteins

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Year:  2013        PMID： 24039022     DOI： 10.1002/anie.201305434

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  12 in total

1.  A KRAS GTPase K104Q Mutant Retains Downstream Signaling by Offsetting Defects in Regulation.

Authors:  Guowei Yin; Samantha Kistler; Samuel D George; Nora Kuhlmann; Leslie Garvey; Minh Huynh; Rachel K Bagni; Michael Lammers; Channing J Der; Sharon L Campbell
Journal:  J Biol Chem       Date:  2017-01-30       Impact factor: 5.157

2.  Atomic-resolution map of the interactions between an amyloid inhibitor protein and amyloid β (Aβ) peptides in the monomer and protofibril states.

Authors:  Moustafa Algamal; Rashik Ahmed; Naeimeh Jafari; Bilal Ahsan; Joaquin Ortega; Giuseppe Melacini
Journal:  J Biol Chem       Date:  2017-08-10       Impact factor: 5.157

Review 3.  Integrative, dynamic structural biology at atomic resolution--it's about time.

Authors:  Henry van den Bedem; James S Fraser
Journal:  Nat Methods       Date:  2015-04       Impact factor: 28.547

4.  Visualizing transient dark states by NMR spectroscopy.

Authors:  Nicholas J Anthis; G Marius Clore
Journal:  Q Rev Biophys       Date:  2015-02       Impact factor: 5.318

Review 5.  NMR methods for exploring 'dark' states in ligand binding and protein-protein interactions.

Authors:  Vitali Tugarinov; Alberto Ceccon; G Marius Clore
Journal:  Prog Nucl Magn Reson Spectrosc       Date:  2021-11-02       Impact factor: 9.795

6.  Identification of functional substates of KRas during GTP hydrolysis with enhanced sampling simulations.

Authors:  Juan Zeng; Jian Chen; Fei Xia; Qiang Cui; Xianming Deng; Xin Xu
Journal:  Phys Chem Chem Phys       Date:  2022-03-30       Impact factor: 3.676

7.  Structure of an inactive conformation of GTP-bound RhoA GTPase.

Authors:  Yuan Lin; Shaoyong Lu; Jian Zhang; Yi Zheng
Journal:  Structure       Date:  2021-01-25       Impact factor: 5.871

8.  Dynamic studies of H-Ras•GTPγS interactions with nucleotide exchange factor Sos reveal a transient ternary complex formation in solution.

Authors:  Uybach Vo; Navratna Vajpai; Kevin J Embrey; Alexander P Golovanov
Journal:  Sci Rep       Date:  2016-07-14       Impact factor: 4.379

9.  Structural impact of GTP binding on downstream KRAS signaling.

Authors:  Dóra K Menyhárd; Gyula Pálfy; Zoltán Orgován; István Vida; György M Keserű; András Perczel
Journal:  Chem Sci       Date:  2020-08-19       Impact factor: 9.825

Review 10.  NMR approaches in structure-based lead discovery: recent developments and new frontiers for targeting multi-protein complexes.

Authors:  David M Dias; Alessio Ciulli
Journal:  Prog Biophys Mol Biol       Date:  2014-08-28       Impact factor: 3.667
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