| Literature DB >> 24038760 |
Jin Huang1, Qiang Zhang, Guang-Zhao Li, David M Haddleton, Russell Wallis, Daniel Mitchell, Andreas Heise, C Remzi Becer.
Abstract
Multivalent binding is a key for many critical biological processes and unique recognition and specificity in binding enables many of different glycans and proteins to work in a great harmony within the human body. In this study, the binding kinetics of synthetic glycopolypeptides to the dendritic cell lectin DC-SIGN and their inhibition potential for DC-SIGN interactions with the gp120 envelope glycoprotein of HIV-1 (gp120) are investigated.Entities:
Keywords: dendritic cells; glycopolymer-lectin interactions; glycopolymers; glycopolypeptides; resonance; surface plasmon
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Year: 2013 PMID： 24038760 DOI： 10.1002/marc.201300439
Source DB: PubMed Journal: Macromol Rapid Commun ISSN： 1022-1336 Impact factor: 5.734