Literature DB >> 24038496

Integration of deworming into an existing immunisation and vitamin A supplementation campaign is a highly effective approach to maximise health benefits with minimal cost in Lao PDR.

Giulia Boselli1, Aya Yajima, Padmasiri Eswara Aratchige, Keith Ernest Feldon, Anonh Xeuatvongsa, Kongxay Phounphenghak, Khampiou Sihakhang, Chanthavisouk Chitsavang, Sylivanh Phengkeo, Albis Francesco Gabrielli, Claudio Politi, Antonio Montresor.   

Abstract

Infection with soil-transmitted helminths (STH) is a major public health problem in many developing countries, with pregnant women and children particularly at risk. Preventive chemotherapy, which is the intervention currently recommended by the WHO against the main helminth infections including those caused by STHs, aims at reducing morbidity through periodical administration of anthelminthic drugs either alone or in combination. The Expanded Programme on Immunization is one of the most widely implemented health programmes in the world and has well established access to children and women. The present study investigated the cost of the provision of anthelminthic drugs during existing immunisation campaigns. In Lao PDR, use of this integrated approach compared with implementation of the vertical deworming campaign alone allowed a reduction of the individual cost of deworming by 10 times (from US$0.23 in the vertical deworming campaign to US$0.03 in the integrated campaign). When drug cost was excluded, the cost of deworming an individual was US$0.007, implying that deworming 100 children would cost less than US$1 if drug donation was in place. The burden posed on health workers by the integration process was perceived as minimal and manageable. Moreover, delivery of anthelminthic drugs during immunisation campaigns enabled campaign teams to observe drug intake directly, which assured safety. These findings prove that integration is an opportunity to maximise health benefits through the delivery of multiple health products and the attainment of high coverage.

Entities:  

Year:  2011        PMID: 24038496      PMCID: PMC5576526          DOI: 10.1016/j.inhe.2011.08.002

Source DB:  PubMed          Journal:  Int Health        ISSN: 1876-3405            Impact factor:   2.473


  8 in total

1.  Childhood mortality impact and costs of integrating vitamin A supplementation into immunization campaigns.

Authors:  P Ching; M Birmingham; T Goodman; R Sutter; B Loevinsohn
Journal:  Am J Public Health       Date:  2000-10       Impact factor: 9.308

Review 2.  Soil-transmitted helminth infections: updating the global picture.

Authors:  Nilanthi R de Silva; Simon Brooker; Peter J Hotez; Antonio Montresor; Dirk Engels; Lorenzo Savioli
Journal:  Trends Parasitol       Date:  2003-12

3.  Maternal and child health: effective entry points for family planning.

Authors:  S Ahmad
Journal:  JOICFP Rev       Date:  1985-10

4.  Soil-transmitted helminthiases: estimates of the number of children needing preventive chemotherapy and number treated, 2009.

Authors: 
Journal:  Wkly Epidemiol Rec       Date:  2011-06-17

5.  Nutritional status of children in the Lao PDR.

Authors:  K Phimmasone; I Douangpoutha; V Fauveau; P Pholsena
Journal:  J Trop Pediatr       Date:  1996-02       Impact factor: 1.165

Review 6.  Nutritional impact of intestinal helminthiasis during the human life cycle.

Authors:  D W T Crompton; M C Nesheim
Journal:  Annu Rev Nutr       Date:  2002-01-04       Impact factor: 11.848

Review 7.  Integration of immunization services with other health interventions in the developing world: what works and why? Systematic literature review.

Authors:  A Wallace; V Dietz; K L Cairns
Journal:  Trop Med Int Health       Date:  2008-11-12       Impact factor: 2.622

8.  Coverage and costs of a school deworming programme in 2007 targeting all primary schools in Lao PDR.

Authors:  Bounlay Phommasack; Khamhoung Saklokham; Chitsavang Chanthavisouk; Viengsavanh Nakhonesid-Fish; Hanne Strandgaard; Antonio Montresor; Dean A Shuey; John Ehrenberg
Journal:  Trans R Soc Trop Med Hyg       Date:  2008-06-12       Impact factor: 2.184

  8 in total
  7 in total

1.  Co-implementing vitamin A supplementation with seasonal malaria chemoprevention in Sokoto State, Nigeria: a feasibility and acceptability study.

Authors:  Olusola Oresanya; Abimbola Phillips; Ekechi Okereke; Abraham Ahmadu; Taiwo Ibinaiye; Madeleine Marasciulo; Charlotte Ward; Olatunde Adesoro; Rilwanu Mohammed; Jamilu Nikau; Chris Osa Isokpunwu; Mohammad Ali Inname; Helen Counihan; Kevin Baker; Kolawole Maxwell; Helen Smith
Journal:  BMC Health Serv Res       Date:  2022-07-05       Impact factor: 2.908

2.  Modeling the economic and epidemiologic impact of hookworm vaccine and mass drug administration (MDA) in Brazil, a high transmission setting.

Authors:  Sarah M Bartsch; Peter J Hotez; Daniel L Hertenstein; David J Diemert; Kristina M Zapf; Maria Elena Bottazzi; Jeffrey M Bethony; Shawn T Brown; Bruce Y Lee
Journal:  Vaccine       Date:  2016-03-18       Impact factor: 3.641

3.  Elimination of morbidity due to soil-transmitted helminthiases among Afghan schoolchildren.

Authors:  Naimullah Safi; Supriya Warusavithana; Sayed Ali Shah Alawi; Hoda Atta; Antonio Montresor; Albis Francesco Gabrielli
Journal:  Acta Trop       Date:  2019-05-22       Impact factor: 3.112

Review 4.  Cost and cost-effectiveness of soil-transmitted helminth treatment programmes: systematic review and research needs.

Authors:  Hugo C Turner; James E Truscott; T Déirdre Hollingsworth; Alison A Bettis; Simon J Brooker; Roy M Anderson
Journal:  Parasit Vectors       Date:  2015-07-03       Impact factor: 3.876

5.  Economic Evaluations of Mass Drug Administration: The Importance of Economies of Scale and Scope.

Authors:  Hugo C Turner; Jaspreet Toor; T Déirdre Hollingsworth; Roy M Anderson
Journal:  Clin Infect Dis       Date:  2018-04-03       Impact factor: 9.079

Review 6.  Are current preventive chemotherapy strategies for controlling and eliminating neglected tropical diseases cost-effective?

Authors:  Hugo C Turner; Wilma A Stolk; Anthony W Solomon; Jonathan D King; Antonio Montresor; David H Molyneux; Jaspreet Toor
Journal:  BMJ Glob Health       Date:  2021-08

Review 7.  Benchmarking the Cost per Person of Mass Treatment for Selected Neglected Tropical Diseases: An Approach Based on Literature Review and Meta-regression with Web-Based Software Application.

Authors:  Christopher Fitzpatrick; Fiona M Fleming; Matthew Madin-Warburton; Timm Schneider; Filip Meheus; Kingsley Asiedu; Anthony W Solomon; Antonio Montresor; Gautam Biswas
Journal:  PLoS Negl Trop Dis       Date:  2016-12-05
  7 in total

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