| Literature DB >> 24037979 |
Elisabeth C W Neefjes1, Maurice J D L van der Vorst, Susanne Blauwhoff-Buskermolen, Henk M W Verheul.
Abstract
Cancer-related fatigue (CRF) is a serious symptom of patients with cancer and deteriorates their daily quality of life. Whereas fatigue is a common problem in the general population, with a prevalence of about 30%, up to 99% of patients with cancer have fatigue of more intense severity. CRF is directly related to the biology of cancer, but it can also be caused by anticancer treatment. We reviewed current evidence about the potential pathophysiological mechanisms causing CRF. Clinical methods to determine the presence and severity of CRF and potential treatment options to reduce CRF will be discussed. After reading this review, the reader will have knowledge of the current understanding of CRF and will be able to give evidence-based advice to patients with CRF.Entities:
Keywords: Drug therapy; Fatigue; Methylphenidate; Modafinil; Neoplasms; Questionnaires
Mesh:
Year: 2013 PMID: 24037979 PMCID: PMC3805156 DOI: 10.1634/theoncologist.2013-0076
Source DB: PubMed Journal: Oncologist ISSN: 1083-7159