Literature DB >> 2403716

Therapeutic trials using tacrine and other cholinesterase inhibitors.

E R Gamzu1, L J Thal, K L Davis.   

Abstract

At this time, the data available on tacrine are inconclusive with respect to efficacy. Preliminary data are often overinterpreted, and it seems prudent to wait for the results of the ongoing multicenter double-blind studies before reaching a definite conclusion about efficacy.

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Year:  1990        PMID： 2403716

Source DB:  PubMed          Journal:  Adv Neurol        ISSN： 0091-3952


  4 in total

1.  Clinical trials in dementia: learning effects with repeated testing.

Authors:  J J Claus; E Mohr; T N Chase
Journal:  J Psychiatry Neurosci       Date:  1991-03       Impact factor: 6.186

2.  Methodologic aspects of a population pharmacodynamic model for cognitive effects in Alzheimer patients treated with tacrine.

Authors:  N H Holford; K E Peace
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-01       Impact factor: 11.205

Review 3.  Tacrine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in Alzheimer's disease.

Authors:  A J Wagstaff; D McTavish
Journal:  Drugs Aging       Date:  1994-06       Impact factor: 3.923

4.  CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 N141I neurons.

Authors:  Maitane Ortiz-Virumbrales; Cesar L Moreno; Ilya Kruglikov; Paula Marazuela; Andrew Sproul; Samson Jacob; Matthew Zimmer; Daniel Paull; Bin Zhang; Eric E Schadt; Michelle E Ehrlich; Rudolph E Tanzi; Ottavio Arancio; Scott Noggle; Sam Gandy
Journal:  Acta Neuropathol Commun       Date:  2017-10-27       Impact factor: 7.801
  4 in total

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