Literature DB >> 24036927

The human foramen magnum--normal anatomy of the cisterna magna in adults.

Nathaniel Whitney1, Hai Sun, Jeffrey M Pollock, Donald A Ross.   

Abstract

INTRODUCTION: The goal of this study was to radiologically describe the anatomical characteristics of the cisterna magna (CM) with regard to presence, dimension, and configuration.
METHODS: In this retrospective study, 523 records were reviewed. We defined five CM types, the range of which covered all normal variants found in the study population. Characteristics of the CM were recorded and correlations between various posterior fossa dimensions and CM volume determined.
RESULTS: There were 268 female (mean age 50.9 ± 16.9 years) and 255 male (mean age 54.1 ± 15.8 years) patients. CM volume was smaller in females than in males and correlated with age (Pearson correlation, r = 0.1494, p = 0.0006) and gender (unpaired t test, r (2) = 0.0608, p < 0.0001). Clivus length correlated with CM volume (Pearson correlation, r = 0.211, p < 0.0001) and gender (unpaired t test, r (2) = 0.2428, p < 0.0001). Tentorial angle did not correlate with CM volume (Pearson correlation, r = -0.0609, p < 0.1642) but did correlate with gender (unpaired t test, r (2) = 0.0163, p < 0.0035). The anterior-posterior dimension of cerebrospinal fluid anterior to the brainstem correlated with CM volume (Pearson correlation, r = 0.181, p < 0.0001) and gender (unpaired t test, r (2) = 0.0205, p = 0.001).
CONCLUSION: The anatomical description and simple classification system we define allows for a more precise description of posterior fossa anatomy and could potentially contribute to the understanding of Chiari malformation anatomy and management.

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Mesh:

Year:  2013        PMID: 24036927     DOI: 10.1007/s00234-013-1269-z

Source DB:  PubMed          Journal:  Neuroradiology        ISSN: 0028-3940            Impact factor:   2.804


  24 in total

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Journal:  J Neurosurg       Date:  2012-09-14       Impact factor: 5.115

6.  Position of cerebellar tonsils in the normal population and in patients with Chiari malformation: a quantitative approach with MR imaging.

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Journal:  Neurology       Date:  2004-03-09       Impact factor: 9.910

Review 9.  [Cisterna megamagna. Dimensions and relations to cerebral atrophy. Clinical and x-ray computed tomographic demonstration].

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10.  Dimensions of the posterior fossa in patients symptomatic for Chiari I malformation but without cerebellar tonsillar descent.

Authors:  Raymond F Sekula; Peter J Jannetta; Kenneth F Casey; Edward M Marchan; L Kathleen Sekula; Christine S McCrady
Journal:  Cerebrospinal Fluid Res       Date:  2005-12-18
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  6 in total

Review 1.  A Historical Review of Brain Drug Delivery.

Authors:  William M Pardridge
Journal:  Pharmaceutics       Date:  2022-06-16       Impact factor: 6.525

2.  Posterior cranial fossa and cervical spine morphometric abnormalities in symptomatic Chiari type 0 and Chiari type 1 malformation patients with and without syringomyelia.

Authors:  Enver I Bogdanov; Aisylu T Faizutdinova; John D Heiss
Journal:  Acta Neurochir (Wien)       Date:  2021-08-27       Impact factor: 2.816

3.  Widespread gene transfer in the central nervous system of cynomolgus macaques following delivery of AAV9 into the cisterna magna.

Authors:  Christian Hinderer; Peter Bell; Charles H Vite; Jean-Pierre Louboutin; Rebecca Grant; Erin Bote; Hongwei Yu; Bryan Pukenas; Robert Hurst; James M Wilson
Journal:  Mol Ther Methods Clin Dev       Date:  2014-12-10       Impact factor: 6.698

4.  Impact of CNS Diseases on Drug Delivery to Brain Extracellular and Intracellular Target Sites in Human: A "WHAT-IF" Simulation Study.

Authors:  Mohammed A A Saleh; Elizabeth C M de Lange
Journal:  Pharmaceutics       Date:  2021-01-13       Impact factor: 6.321

5.  In-depth characterization of neuroradiological findings in a large sample of individuals with autism spectrum disorder and controls.

Authors:  Sara Ambrosino; Hasnaa Elbendary; Maarten Lequin; Dominique Rijkelijkhuizen; Tobias Banaschewski; Simon Baron-Cohen; Nico Bast; Sarah Baumeister; Jan Buitelaar; Tony Charman; Daisy Crawley; Flavio Dell'Acqua; Hannah Hayward; Rosemary Holt; Carolin Moessnang; Antonio M Persico; Roberto Sacco; Antonia San José Cáceres; Julian Tillmann; Eva Loth; Christine Ecker; Bob Oranje; Declan Murphy; Sarah Durston
Journal:  Neuroimage Clin       Date:  2022-07-16       Impact factor: 4.891

6.  An increase in the posterior subarachnoid space accelerates the timing of syrinx resolution after foramen magnum decompression of type I Chiari malformation.

Authors:  Yuichiro Ohnishi; Sho Fujiwara; Tomofumi Takenaka; Saki Kawamoto; Koichi Iwatsuki; Haruhiko Kishima
Journal:  Sci Rep       Date:  2021-09-27       Impact factor: 4.379

  6 in total

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