Literature DB >> 24035880

Prediction of early and late complications after oral mucosal graft harvesting: multivariable analysis from a cohort of 553 consecutive patients.

Guido Barbagli1, Nicola Fossati2, Salvatore Sansalone3, Alessandro Larcher2, Giuseppe Romano1, Vincenzo Dell'Acqua2, Giorgio Guazzoni2, Massimo Lazzeri4.   

Abstract

PURPOSE: We investigated the early and late complications after oral mucosal graft harvesting, and reported the independent predictors of outcome via multivariable analysis.
MATERIALS AND METHODS: We performed a retrospective descriptive study of 553 patients from whom an oral mucosa graft was harvested for urethroplasty from single or bilateral cheeks. Patients who underwent oral mucosa harvesting from the lip, the tongue or from the cheek and lip at the same time were excluded from analysis. The oral graft was harvested in an ovoid shape with closure of the wound. Postoperative early and late complications were investigated using a self-administered, nonvalidated, semiquantitative questionnaire. There were 6 questions on early complications, and 13 questions investigated late complications and patient satisfaction.
RESULTS: Descriptive statistics of categorical variables focused on frequencies and proportions. Univariable and multivariable analyses were used to predict early and late dissatisfaction of patients. Bleeding was reported in 3.4% of patients. Overall 53.2% of patients did not report any pain and 36.3% reported no swelling. Late complications analysis showed that 95.5% of patients declared that the surgical closure of the wound did not cause any difficulty in opening the mouth or problems with smiling (98.2%) and/or dry mouth (95.8%). Overall 98.2% of patients were satisfied with the procedure. Univariable and multivariable analyses revealed that bilateral graft harvesting was the only significant predictor of patient dissatisfaction (OR 2.85, p = 0.01 and OR 2.72, p = 0.02; respectively).
CONCLUSIONS: Harvesting the oral mucosa ovoid graft from a single cheek with closure of the wound is a safe procedure with high rates of patient satisfaction.
Copyright © 2014 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  cheek; mouth mucosa; postoperative complications; questionnaires; urethra

Mesh:

Year:  2013        PMID: 24035880     DOI: 10.1016/j.juro.2013.09.006

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  14 in total

Review 1.  What is the role of single-stage oral mucosa graft urethroplasty in the surgical management of lichen sclerosus-related stricture disease in men? A systematic review.

Authors:  Francesco Esperto; Wesley Verla; Achilles Ploumidis; Rachel Barratt; Roberto La Rocca; Nicolaas Lumen; Yuhong Yuan; Felix Campos-Juanatey; Tamsin Greenwell; Francisco Martins; Nadir Osman; Silke Riechardt; Marjan Waterloos; Konstantinos Dimitropoulos
Journal:  World J Urol       Date:  2021-08-26       Impact factor: 4.226

Review 2.  Graft surgery in extensive urethral stricture disease.

Authors:  Miroslav L Djordjevic
Journal:  Curr Urol Rep       Date:  2014-08       Impact factor: 3.092

3.  Patient-reported outcomes for typical single cheek harvesting vs atypical lingual, labial or bilateral cheeks harvesting: a single-center analysis of more than 800 patients.

Authors:  Guido Barbagli; Marco Bandini; Sofia Balò; Francesco Montorsi; Salvatore Sansalone; Mauro De Dominicis; Denis Butnaru; Massimo Lazzeri
Journal:  World J Urol       Date:  2020-08-08       Impact factor: 4.226

4.  A novel composite two-stage urethroplasty for complex penile strictures: A multicenter experience.

Authors:  Pankaj M Joshi; Guido Barbagli; Vikram Batra; Sandesh Surana; Atef Hamouda; Salvatore Sansalone; Dimitris Costi; Massimo Lazzeri; Craig Hunter; Devang J Desai; Fabio Castiglione; Sanjay B Kulkarni
Journal:  Indian J Urol       Date:  2017 Apr-Jun

5.  Single-stage tubular urethral reconstruction using oral grafts is an alternative to classical staged approach for selected penile urethral strictures.

Authors:  Felix Campos-Juanatey; Simon Bugeja; Mariya Dragova; Anastasia V Frost; Stella L Ivaz; Daniela E Andrich; Anthony R Mundy
Journal:  Asian J Androl       Date:  2020 Mar-Apr       Impact factor: 3.285

6.  The long-term results of lingual mucosal grafts for repairing long anterior urethral strictures.

Authors:  Hussein Abdelhameed; Samir Elgamal; Mohamed A Farha; Ahmed El-Abd; Ahmed Tawfik; Mohamed Soliman
Journal:  Arab J Urol       Date:  2015-02-07

7.  Editorial - The case for excision and primary anastomotic urethroplasty for bulbar urethral stricture.

Authors:  Jordan A Siegel; Allen F Morey
Journal:  Int Braz J Urol       Date:  2016 Sep-Oct       Impact factor: 1.541

8.  Substitution urethroplasty or anastomotic urethroplasty for bulbar urethra strictures? Or endoscopic urethrotomy? Opinion: Anastomotic Urethroplasty.

Authors:  Jordan A Siegel; Allen F Morey
Journal:  Int Braz J Urol       Date:  2015 Jul-Aug       Impact factor: 1.541

Review 9.  History and evolution of the use of oral mucosa for urethral reconstruction.

Authors:  Guido Barbagli; Sofia Balò; Francesco Montorsi; Salvatore Sansalone; Massimo Lazzeri
Journal:  Asian J Urol       Date:  2016-06-26

Review 10.  Surgical treatment of bulbar urethral strictures: tips and tricks.

Authors:  Guido Barbagli; Marco Bandini; Sofia Balò; Salvatore Sansalone; Denis Butnaru; Massimo Lazzeri
Journal:  Int Braz J Urol       Date:  2020 Jul-Aug       Impact factor: 1.541

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