Harvey S Uy1, Kenneth R Kenyon. 1. From Philippine General Hospital (Uy), University of the Philippines, Manila, St. Luke's Medical Center (Uy), Quezon City, and the Pacific Eye and Laser Institute (Uy), Makati, Philippines; Harvard Medical School, Tufts University School of Medicine, and Schepens Eye Research Institute (Kenyon), Boston, Massachusetts, USA. Electronic address: harveyuy@yahoo.com.
Abstract
PURPOSE: To compare the anatomic and refractive outcomes in eyes having phacoemulsification with 1 of 3 clear corneal incision (CCI) closure methods. SETTING: Ambulatory surgical center, Makati, Philippines. DESIGN: Prospective randomized clinical trial. METHODS:Patients having phacoemulsification cataract surgery hadwound closure using no additional treatment (control), a single 10-0 nylon suture, or a liquid adhesive ocular bandage (Ocuseal). The main outcome measures were wound-edge closure rates, surgically induced astigmatism (SIA), foreign-body sensation, and intraocular pressure (IOP) 1, 3, 5, 7, and 14 days postoperatively. RESULTS: The study evaluated 90 eyes. There was a significant improvement in wound-edge closure rates in the suture group and the ocular bandage group compared with the control group (P<.001). A significant increase in SIA occurred in the sutured group but not in the control or ocular bandage groups (P<.001). The ocular bandage group had significantly less foreign-body sensation than the control and suture groups (P<.001). There were no significant differences in IOP between the groups (P=.515). CONCLUSIONS: The liquid adhesive ocular bandage resulted in improved wound-edge closure, reduced SIA, and diminished foreign-body sensation. Suturing was associated with improved wound-edge closure but increased SIA and foreign-body sensation. Unsutured incisions led to delayed wound-edge closure and increased foreign-body sensation.
RCT Entities:
PURPOSE: To compare the anatomic and refractive outcomes in eyes having phacoemulsification with 1 of 3 clear corneal incision (CCI) closure methods. SETTING: Ambulatory surgical center, Makati, Philippines. DESIGN: Prospective randomized clinical trial. METHODS:Patients having phacoemulsification cataract surgery had wound closure using no additional treatment (control), a single 10-0 nylon suture, or a liquid adhesive ocular bandage (Ocuseal). The main outcome measures were wound-edge closure rates, surgically induced astigmatism (SIA), foreign-body sensation, and intraocular pressure (IOP) 1, 3, 5, 7, and 14 days postoperatively. RESULTS: The study evaluated 90 eyes. There was a significant improvement in wound-edge closure rates in the suture group and the ocular bandage group compared with the control group (P<.001). A significant increase in SIA occurred in the sutured group but not in the control or ocular bandage groups (P<.001). The ocular bandage group had significantly less foreign-body sensation than the control and suture groups (P<.001). There were no significant differences in IOP between the groups (P=.515). CONCLUSIONS: The liquid adhesive ocular bandage resulted in improved wound-edge closure, reduced SIA, and diminished foreign-body sensation. Suturing was associated with improved wound-edge closure but increased SIA and foreign-body sensation. Unsutured incisions led to delayed wound-edge closure and increased foreign-body sensation.
Authors: Jackie Tan; Leslie John Ray Foster; Frank James Lovicu; Stephanie Louise Watson Journal: J Cataract Refract Surg Date: 2022-03-01 Impact factor: 3.528
Authors: Benjamin G Cooper; Rachel C Stewart; Deborah Burstein; Brian D Snyder; Mark W Grinstaff Journal: Angew Chem Int Ed Engl Date: 2016-03-02 Impact factor: 15.336