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Literature DB >> 2403534

Evidence for three separate genes encoding the proteins of the mycobacterial antigen 85 complex.

H G Wiker¹, K Sletten, S Nagai, M Harboe.

Abstract

The secreted Mycobacterium bovis BCG antigen 85 complex, which is known to bind to human fibronectin, consists of three closely related cross-reacting antigens. Amino-terminal sequence analysis of the purified proteins showed distinct differences. Data are presented to show that the three components are produced by individual cells, which indicates that three separate genes are involved.

Entities: Gene Species

Mesh：

Substances：

Year: 1990 PMID： 2403534 PMCID： PMC258444 DOI： 10.1128/iai.58.1.272-274.1990

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

21 in total

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8. Cross-reactions between mycobacteria. II. Crossed immunoelectrophoretic analysis of soluble antigens of BCG and comparison with other mycobacteria.

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31 in total

1. Humoral immune response of tuberculous patients against the three components of the Mycobacterium bovis BCG 85 complex separated by isoelectric focusing.

Authors: J P Van Vooren; A Drowart; M De Cock; A Van Onckelen; M H D'Hoop; J C Yernault; C Valcke; K Huygen
Journal: J Clin Microbiol Date: 1991-10 Impact factor: 5.948

2. Nucleotide sequence of the 32 kDa-protein gene (antigen 85 A) of Mycobacterium bovis BCG.

Authors: L De Wit; A de la Cuvellerie; J Ooms; J Content
Journal: Nucleic Acids Res Date: 1990-07-11 Impact factor: 16.971

3. Purification of Mycobacterium bovis BCG Tokyo antigens by chromatofocusing, lectin-affinity chromatography, and hydrophobic interaction chromatography.

Authors: E A Sugden; K Stilwell; D C Watson; E B Rohonczy; P Martineau
Journal: Clin Diagn Lab Immunol Date: 1996-09

4. Protein G-based enzyme-linked immunosorbent assay for anti-MPB70 antibodies in bovine tuberculosis.

Authors: M Harboe; H G Wiker; J R Duncan; M M Garcia; T W Dukes; B W Brooks; C Turcotte; S Nagai
Journal: J Clin Microbiol Date: 1990-05 Impact factor: 5.948

5. Enoyl-coenzyme A hydratase and antigen 85B of Mycobacterium habana are specifically recognized by antibodies in sera from leprosy patients.

Authors: J Serafín-López; M Talavera-Paulin; J C Amador-Molina; M Alvarado-Riverón; M M Vilchis-Landeros; P Méndez-Ortega; M Fafutis-Morris; V Paredes-Cervantes; R López-Santiago; C I León; M I Guerrero; R M Ribas-Aparicio; G Mendoza-Hernández; C Carreño-Martínez; S Estrada-Parra; I Estrada-García
Journal: Clin Vaccine Immunol Date: 2011-05-25

6. Cloning and sequencing of the gene for alpha antigen from Mycobacterium avium and mapping of B-cell epitopes.

Authors: N Ohara; K Matsuo; R Yamaguchi; A Yamazaki; H Tasaka; T Yamada
Journal: Infect Immun Date: 1993-04 Impact factor: 3.441

7. Fibronectin-binding antigen 85 and the 10-kilodalton GroES-related heat shock protein are the predominant TH-1 response inducers in leprosy contacts.

Authors: P Launois; M N N'Diaye; J L Cartel; I Mane; A Drowart; J P Van Vooren; J L Sarthou; K Huygen
Journal: Infect Immun Date: 1995-01 Impact factor: 3.441

8. T cell response to purified filtrate antigen 85 from Mycobacterium bovis Bacilli Calmette-Guérin (BCG) in leprosy patients.

Authors: P Launois; K Huygen; J De Bruyn; M N'Diaye; B Diouf; L Sarthouj; J Grimaud; J Millan
Journal: Clin Exp Immunol Date: 1991-11 Impact factor: 4.330

9. Identification and characterization of epitopes shared between the mycobacterial 65-kilodalton heat shock protein and the actively secreted antigen 85 complex: their in situ expression on the cell wall surface of Mycobacterium leprae.

Authors: A Rambukkana; P K Das; J D Burggraaf; W R Faber; P Teeling; S Krieg; J E Thole; M Harboe
Journal: Infect Immun Date: 1992-11 Impact factor: 3.441

10. Chromatographic purification and characterization of antigens A and D from Mycobacterium paratuberculosis and their use in enzyme-linked immunosorbent assays for diagnosis of paratuberculosis in sheep.

Authors: E A Sugden; B W Brooks; N M Young; D C Watson; K H Nielsen; A H Corner; C Turcotte; A Michaelides; R B Stewart
Journal: J Clin Microbiol Date: 1991-08 Impact factor: 5.948