| Literature DB >> 24034692 |
Aristidis Moustakas1, Carl-Henrik Heldin.
Abstract
In this issue, Zhang et al. (2013) demonstrate that the ubiquitin ligase TRAF4 associates with the TGF-β receptors, rescuing them from degradation and ubiquitylating TAK1 to activate non-Smad signaling, which together promote metastasis of breast cancer cells.Entities:
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Year: 2013 PMID： 24034692 DOI： 10.1016/j.molcel.2013.08.034
Source DB: PubMed Journal: Mol Cell ISSN： 1097-2765 Impact factor: 17.970