Literature DB >> 24034240

Self-eating limits EGFR-dependent tumor growth.

Valeria R Fantin1, Robert T Abraham.   

Abstract

Autophagy is a cell-autonomous, catabolic process that plays context-dependent roles in tumor growth and progression. Wei et al. report that EGFR signaling promotes tumor growth through phosphorylation and functional inactivation of Beclin 1 and the consequent suppression of autophagy.
Copyright © 2013 Elsevier Inc. All rights reserved.

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Year:  2013        PMID： 24034240     DOI： 10.1016/j.cell.2013.08.040

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  5 in total

Review 1.  Beth Levine's Legacy: From the Discovery of BECN1 to Therapies. A Mentees' Perspective.

Authors:  Zhenyi An; Wei-Chung Chiang; Álvaro F Fernández; Luis H Franco; CongCong He; Shu-Yi Huang; Eunmyong Lee; Yang Liu; Salwa Sebti; Sanae Shoji-Kawata; Shyam Sirasanagandla; Richard C Wang; Yongjie Wei; Yuting Zhao; Silvia Vega-Rubin-de-Celis
Journal:  Front Cell Dev Biol       Date:  2022-06-27

2.  Inhibition of autophagy induced by quercetin at a late stage enhances cytotoxic effects on glioma cells.

Authors:  Yunke Bi; Chen Shen; Chenguang Li; Yaohua Liu; Dandan Gao; Chen Shi; Fei Peng; Zhendong Liu; Boxian Zhao; Zhixing Zheng; Xiaoxiong Wang; Xu Hou; Huailei Liu; Jianing Wu; Huichao Zou; Kaikai Wang; Chen Zhong; Jiakang Zhang; Changbin Shi; Shiguang Zhao
Journal:  Tumour Biol       Date:  2015-10-10

3.  Role of hypoxia-inducible factor-1α and CD146 in epidermal growth factor receptor-mediated angiogenesis in salivary gland adenoid cystic carcinoma.

Authors:  Wei-Ming Wang; Zhi-Li Zhao; Wen-Feng Zhang; Yi-Fang Zhao; Lu Zhang; Zhi-Jun Sun
Journal:  Mol Med Rep       Date:  2015-05-22       Impact factor: 2.952

4.  MiR-143 inhibits EGFR-signaling-dependent osteosarcoma invasion.

Authors:  Qiang Wang; Jun Cai; Jingcheng Wang; Chuanzhi Xiong; Jianning Zhao
Journal:  Tumour Biol       Date:  2014-09-17

5.  A novel multikinase inhibitor R8 exhibits potent inhibition on cancer cells through both apoptosis and autophagic cell death.

Authors:  Yuqiong Xie; Chunchun Li; Yali Huang; Zhenyu Jia; Jiang Cao
Journal:  Oncotarget       Date:  2017-08-14
  5 in total

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