BACKGROUND: Among the strategies to increase the number of lung transplants, ex vivo lung perfusion (EVLP) represents a novel technique to expand the donor pool. METHODS: Data from donors referred to our center were retrospectively analyzed to identify grafts that could potentially be potentially reconditioned by EVLP and for comparison with those obtained by clinical application of EVLP program in our center. RESULTS: Among 75 rejected lungs, 23 organs have been identified as potentially treatable with EVLP with a hypothetic increase of lung transplant activity of 53%. After the introduction of the EVLP program in our center, lung transplantation with reconditioned grafts was performed in 7 (23%) patients with a 30% increase in transplant procedures. CONCLUSION: Although less than expected, EVLP increased the number of lungs suitable for transplantation.
BACKGROUND: Among the strategies to increase the number of lung transplants, ex vivo lung perfusion (EVLP) represents a novel technique to expand the donor pool. METHODS: Data from donors referred to our center were retrospectively analyzed to identify grafts that could potentially be potentially reconditioned by EVLP and for comparison with those obtained by clinical application of EVLP program in our center. RESULTS: Among 75 rejected lungs, 23 organs have been identified as potentially treatable with EVLP with a hypothetic increase of lung transplant activity of 53%. After the introduction of the EVLP program in our center, lung transplantation with reconditioned grafts was performed in 7 (23%) patients with a 30% increase in transplant procedures. CONCLUSION: Although less than expected, EVLP increased the number of lungs suitable for transplantation.
Authors: Amit Bery; Gary Marklin; Akinobu Itoh; Daniel Kreisel; Tsuyoshi Takahashi; Bryan F Meyers; Ruben Nava; Benjamin D Kozower; Hailey Shepherd; G Alexander Patterson; Varun Puri Journal: Ann Thorac Surg Date: 2021-01-07 Impact factor: 5.102
Authors: Danielle M Peterson; Eliza W Beal; Brenda F Reader; Curtis Dumond; Sylvester M Black; Bryan A Whitson Journal: ASAIO J Date: 2022-01-20 Impact factor: 3.826
Authors: Anders S I Andreasson; Lee A Borthwick; Colin Gillespie; Kasim Jiwa; Jonathan Scott; Paul Henderson; Jonny Mayes; Rosalba Romano; Marius Roman; Simi Ali; James E Fildes; Nandor Marczin; John H Dark; Andrew J Fisher Journal: J Heart Lung Transplant Date: 2017-05-12 Impact factor: 10.247
Authors: Anders S I Andreasson; Danai M Karamanou; Colin S Gillespie; Faruk Özalp; Tanveer Butt; Paul Hill; Kasim Jiwa; Hannah R Walden; Nicola J Green; Lee A Borthwick; Stephen C Clark; Henning Pauli; Kate F Gould; Paul A Corris; Simi Ali; John H Dark; Andrew J Fisher Journal: Eur J Cardiothorac Surg Date: 2017-03-01 Impact factor: 4.191